Te whakatupuranga hou o NSAIDs: arotake, utu rārangi

He rota o te huringa pathological e puta i roto i te tinana, haere tahi i te mamae. Ki te aro i taua tohu whakawhanakehia NSAIDs ranei kore-steroidal anti-inflammatory kaihoko. E pai pohe to ratou, whakaiti mumura, whakaiti ngawhatanga. Heoi, he maha taero i ngā pānga taha. tauwhāiti tenei te taea o ratou te whakamahi mō te tahi mau tūroro. Kua whakawhanakehia Pūtaiao Modern te whakatupuranga hou o NSAIDs. He nui iti pea ki te meinga tauhohe kino taua raau taero, engari noho taero whai hua ki te mamae.

te pānga o te parau tumu o

He aha te mea te reira e tika ana ki te pānga o NSAIDs i runga i te tinana? mahi ratou i runga i te cyclooxygenase. E rua isoforms Cox. e waha ana ia o ratou i ona mahi. Taua whākōkī (Cox) ai te tauhohenga matū hua i roto i te waikawa arachidonic haere ki prostaglandins, thromboxanes me leukotrienes.

Cox-1 Ko kawenga mo te hanga o prostaglandins. tiaki ratou te puku i te pānga kino i te pānga i runga i te mahi o platelets, me te pānga o te huringa i roto i te rere toto tākihi.

Ko te tikanga ngaro Cox-2 me ko te mumura paru motuhake synthesized i roto i cytotoxins, me te tahi atu kaitakawaenga.

Taua mahi o NSAIDs rite inhibition o Cox-1, te maua e te plurality o te taha-pānga.

whanaketanga hou

Ko reira kahore he mea ngaro e nga whakatakataka a te whakatupuranga tuatahi o NSAIDs i te pānga kino i runga i te mucosa pekitīlia. Na reira, kua whakatakotoria e kaipūtaiao te whāinga - ki te whakaiti i te pānga houhou. I whakawhanakehia he puka tuku hou. I roto i taua formulations ko te whakauru kaha i roto i te kōpaki motuhake. I hanga te capsule o taua rauemi e kore e e tareka i te taiao waikawa o te puku. ka anga ratou ki te hinga noa, i te patu i roto i te punuatuna. Ko taea ki te whakaiti i te pānga irritating i runga i te mucosa pekitīlia. Heoi, kei te tiaki tonu tikanga o whara kino taiepa wahi gastrointestinal.

Tenei ue'i synthesized Utaina he pūhui rawa hou. rongoā o mua e ratou tikanga faufaa rerekē o te mahi. he whakatupuranga hou o NSAIDs āhuatanga e te pānga whiriwhiri i runga i Cox-2, kia rite ki te pai kia rite ki te inhibition o prostaglandin production. Tenei taea ki a koe tae pānga e tika ana katoa - analgesic, antipyretic, anti-inflammatory. I roto i tenei take, ki te whakatupuranga hou o NSAIDs whakaiti te pānga i runga i te toto coagulation, mahi mōtepe mucosa pekitīlia.

pānga Anti-inflammatory tika ki uruhanga raro o taiepa iaia, me te he hekenga i roto i te whakaputa i te whānuitanga o ngā kaitakawaenga inflammatory. Nā ki tenei puaretanga whakamōkitohia te ritenga o receptors karere mamae. Pānga i runga i etahi pokapū thermoregulatory i te roro, tukua te whakatupuranga hou o NSAIDs he pai ki te raro i te pāmahana whānui.

Tuhinga

Whānuitia mohiotia pānga o NSAIDs. hāngai ana te pānga o taua raau taero te i ārai whakaiti tukanga inflammatory ranei. Enei taero whakahere he pānga antipyretic pai. Ka taea te whakaritea o ratou pānga i runga i te tinana ki te pānga o Pë whakapōauau. I tua atu, whakarato ratou he analgesic, pānga anti-inflammatory. NSAIDs tutuki ai tauine whānui i roto i te tautuhinga haumanu, me te i roto i te ora ia rā. I teie mahana, ko reira tetahi o nga taero tino rongonui hauora.

tuhia te whai pānga pai te i runga i te āhuatanga e whai ake nei:

1. Diseases o te pūnaha musculoskeletal. I ngā takoki, karawarawa, he koha noa raraunga rumati rongoā. NSAIDs whakamahia i roto i te osteochondrosis, arthropathy inflammatory, rumati. He pānga anti-inflammatory i roto i te scoliosis, kōpae herniated te tarukino.
2. mamae kino. Teuteu rawa pai whakamahia i roto i te colic biliary, ngā māuiui gynecology. whakakore ratou nga pāhoahoa, ara migraines, tākihi hūhi. Kei te pai te whakamahia NSAIDs mō ngā tūroro i roto i te wā postoperative.
3. High pāmahana. pānga antipyretic taea te whakamahi o te raau taero i roto i te ma'i āhua kanorau o e rua ngā pakeke me ngā tamariki. He whai hua ēnei taero noa i te kirika.
4. hanganga Thrombus. NSAIDs he drugs antiplatelet. Tenei e āhei ki a ratou te tono i roto i te ischemia. Ko ratou he mehua ārai ki te whakaeke ngakau, me te patu.

whakarōpū

Mō 25 matahiti i ma'iri a'e, i hangaia ai 8 anake rōpū o NSAIDs. I teie mahana, kua nui haere taua tau ki te 15. Heoi, e kore e tangohia te ahua tangohia noa i huaina tākuta. Putanga i runga i te mākete, hohoro riro rongonui whānui o NSAIDs. Teuteu turakina Pë opioid. No te mea ratou, i rite ki te mua, kihai i whakapataritari whārua romahā.

Ko te whakarōpū o NSAIDs tā te wehenga ki e rua ngā rōpū:

1. taero pakeke (whakatupuranga tuatahi). Tenei kāwai ngā taero mohiotia, "Tsitramon", "ahipirini", "Ibuprofen", "naproxen", "Nurofen", "Voltaren", "Diklak", "diclofenac", "indomethacin", "Movimed", "Phenylbutazone" .
2. NSAIDs New (whakatupuranga tuarua). Neke atu i te te 15-20 tau mua, kua whakawhanakehia Pūtaiao hua pai, pērā i "Movalis", "Nimesil", "Nise", "Celebrex" "Arcoxia."

Heoi, e kore te mea anake te whakarōpū o NSAIDs tenei. E wehea drugs whakatupuranga hou ki pärönaki waikawa-kore, me te waikawa. I te tīmatanga, whakaaro te kāwai whakamutunga:

1. Salicylates. Kei roto i tēnei rōpū i te raau taero NSAID, "ahipirini", "diflunisal," "Lizinmonoatsetilsalitsilat".
2. Pyrazolidine. Māngai o tenei kāwai o raau taero e "phenylbutazone", "azapropazone", "oxyphenbutazone."
3. Oxicams. Ko te whakatupuranga hou tino auaha o NSAIDs tenei. Rārangi o raau taero: "piroxicam" "Meloxicam", "Lornoxicam", "tenoxicam". e kore e cheap rongoā, ko ratou pānga i runga i te tinana pumau nui roa atu te tahi atu NSAIDs.
4. pärönaki waikawa Phenylacetic. he rōpū taua o NSAIDs ngā tikanga "diclofenac", "tolmetin," "Indomethacin", "Etodolac", "Sulindac," "Atseklofenak".
5. Formulations waikawa anthranilic. Ko te māngai matua o te rongoā "Mefenaminat".
6. Founga o te waikawa propionic. maha NSAIDs ataahua Kei tēnei kāwai. Rārangi o raau taero: "Ibuprofen" "ketoprofen" "benoxaprofen", "fenbufen," "fenoprofen," "waikawa tiaprofenic", "naproxen", "Flurbiprofen", "pirprofen," "nabumetone".
7. pärönaki waikawa Isonicotinic. rongoā Main "Amizon".
8. raau taero pyrazolone. Ki tenei kāwai no ki te tikanga pai-mohiotia, "Analgin".

Na roto i te waikawa-kore pärönaki ngā sulfonamides. Tenei rōpū ngā taero, "Rofecoxib" "Celecoxib", "Nimesulide".

pānga taha

he whakatupuranga hou o NSAIDs whakarārangitia i runga ake, rerekē mana whai hua i runga i te tinana. Heoi, e kore ratou e pā i te mahi o te wahi gastrointestinal. Titore enei taero ko tetahi wāhi pai: ko te whakatupuranga hou o NSAIDs kore e whai i te tino kaha te paheketanga i runga i te kiko wheua ngohe.

Heoi, ara taua he whai hua rawa e taea o whakapataritari he maha o ngā pānga houhou. kia ratou e mohio, rawa, ki te te whakamahia te tarukino mo te wa roa.

kia ngā te pānga taha matua:

• whanoke;
• te momoe;
• ānini;
• rohirohi;
• palpitations ngakau;
• te whakanui ake te pēhanga;
• he hāhā iti o te manawa;
• mare maroke;
• disorders kūnatu;
• pūmua i roto i te mimi;
• whākōkī ate teitei;
• ponana kiri (ira);
• pupuri inu;
• mate pāwera.

I roto i tenei take, e kore e kitea te kino mucosa pekitīlia i roto i te whakauru o NSAIDs hou. E kore e nga taero meinga exacerbation o te toto mariao.

Tūtohutanga mō te whakamahi

Ko te pai taero anti-inflammatory i phenylacetic waikawa, salicylates, pirazolidony, oxicams, alkanones, taero o te waikawa propionic me sulfonamide.

Mai i te mamae tahi tino tōtika faaore taero "Indomethacin", "diclofenac", "Ketoprofen", "Flurbiprofen". Ko te NSAID pai i roto i te osteochondrosis tenei. Ko te rongoa i runga atu atu i "ketoprofen" faaineineraa riro korerotia pānga anti-inflammatory. tikanga "piroxicam" taka ki tenei kāwai.

Pë tōtika e "Ketorolac" taero "Ketoprofen", "Indomethacin" "Diclofenac".

Ko te rangatira i roto i te whakatupuranga hou o NSAIDs ko te tarukino "Movalis". tukua ana tēnei taputapu te ki te tono i te wā roa. taero Anti-inflammatory e whai hua analogs taero "Movasin", "Mirloks", "lem", "Artrozan", "Melox", "Melbek", "Mesipol" me "Amelotex".

Drug "Movalis"

He wātea rite papa, suppositories me otinga rectal mō te whakahaere intramuscular tēnei tarukino. E pā ana Māngai ki te waikawa pärönaki enolovoy. Āhuatanga analgesic tarukino pai me ngā āhuatanga antipyretic. I kitea te reira i e i roto i ngā tukanga tata inflammatory katoa hopoi mai te rongoā he pānga painga.

Tuhinga mō te whakamahi o taero he osteoarthritis, ankylosing spondylitis, kaikōiwi.

Heoi, kia mōhio e reira e contraindications ki te māngai riro:

• hypersensitivity ki tetahi wae o te rongoā;
• mate whai puku i roto i te wā whakapeka;
• nui waimaerotanga tākihi;
• whewhe toto;
• nui rahunga ate;
• hapū, uma-kai;
• kore ngakau kino.

Kaua e tangohia e te tamariki tarukino ki runga, ki te 12 tau.

tūroro Pakeke nei e pāngia osteoarthritis, tūtohutia ia i te 7.5 mg. Ki te tika, kia nui haere tenei horopeta i te 2 ngā wā.

I roto i te kaikōiwi me ankylosing spondylitis täkupu rā ko te 15 mg.

kia tango tiaki Extreme te tarukino ki tūroro e e pängia ana ki te putanga o ngā pānga taha. Iwi e Kua whakahuatia iti hoki tākihi me te hunga e ki runga ki tātari toto, kia tango kaua e nui ake 7.5 mg i roto i te ra.

Ko te utu o te tarukino "Movalis" i roto i te papa o 7.5 mg, № 20 Ko 502 moni.

Kiritaki whakaaro e pā ana ki te rongoā

Reviews o iwi maha nei e ngohengohe mamae kino ki, whakaatu e te tarukino "Movalis" - te taputapu pai hoki te whakamahi wā roa-. Kei te pai te noatia te reira e te tūroro. I tua atu, tona aroaro roa i roto i te tinana hanga taea reira ki horopeta kotahi o te rongoā. He take tino nui, kia rite ki te nuinga o kiritaki, ko ki te tiaki i te ngohe, no te mea kua kahore pānga tōraro ki runga ki a ratou i te tarukino. He mea tino nui mō te tūroro e kua whakamahia te tikanga i roto i te osteochondrosis, arthrosis.

I tua atu, he pai te tarukino whakaora i ngā mamae - niho tunga, ānini. Kia whai whakaaro motuhake ki te tūroro i runga i te rārangi faahiahia o ngā pānga taha. I te fariiraa i te maimoatanga NSAID ahakoa whakatupato i te kaiwhakanao, kahore faingataa nunu'a kino.

Drug "Celecoxib"

hāngai ana te mahi o tenei taputapu kei i tamarыraa i te huru o te manawanui ki osteochondrosis me arthrosis. Ko maitai te tarukino faaore mamae, tōtika relieves te tukanga inflammatory. pānga kino i runga i te pūnaha kūnatu Kua tāutuhia.

Tuhinga mō te whakamahi i homai i roto i te buka haapiiraa e:

• rumati psoriatic ;
• osteoarthritis;
• kaikōiwi;
• spondylitis ankylosing.

he maha o contraindications tenei waihanga kua. I tua atu, e kore e te tarukino tikanga mō ngā tamariki i raro i te 18 tau. kia whai tūpato hei maharatanga mo te iwi e whai kore ngakau pāngia rite te tikanga o te whakanui ake susceptibility ki pupuri inu.

Ko te utu o te tarukino rerekē i runga i te mōkihi, i roto i te rohe o 500-800 moni.

whakaaro kiritaki

arotake Tino whakahē e pā ana ki tenei rongoā. Ētahi tūroro hoki o tenei whare i taea e riro mamae tahi. Ētahi atu tūroro mea e kore i te āwhina i te tarukino. Ko te kupu, e kore te mea whai hua tonu tenei tikanga.

I tua atu, e kore matou e tango i te tarukino ratou. I roto i te tahi mau whenua Pākehā rāhuitia tenei rongoā te no te mea te pānga o cardiotoxicity, i te mea nui hoki te ngakau paa kino.

Drug "Nimesulide"

Tenei rongoā kore anake he pānga anti-inflammatory me antipain. He āhuatanga antioxidant e tautāwhi i matū raau e whakangaro wheua ngohe me te collagen muka Founga.

Tono rongoa hoki:

• kaiponapona;
• kaiponapona;
• osteoarthritis;
• myalgia;
• arthralgia;
• bursitis;
• kirika;
• ngā syndromes mamae.

I roto i tenei take, te pānga analgesic o te tarukino whakarato rawa nohopuku. Tikanga, mana'o te manawanui te tauturu i roto i te 20 meneti i muri i ingestion. Ko te aha te mea tino whai hua mō te mamae paroxysmal whakapeka tenei taputapu.

Tata tonu, i pai noatia te tarukino i tūroro. Ko ētahi wā, kia wheako koe ngā pānga taha pērā i whanoke, te momoe, ānini, whakapairuaki, tokopā, hematuria, oliguria, urticaria.

E kore e whakaaetia te taputapu ki te riro hapu wahine me ngā tamariki ki runga, ki te 12 tau. kia tango tiaki Special te tarukino "Nimesulide" iwi i kite nei i takawhita, mahi tākihi waimaero, kite ngakau ranei.

raau taero Utu i runga i toharite 76,9 moni.

He aha te mahi kiritaki?

Reviews o te faaineineraa he pai tata tonu. Mai te mea maitai te tarukino relieves mamae, me te whakaiti kirika, nui whawhai mumura.

pūrongo maha tūroro e puta tohu te tauturu hohoro nui, me te roanga o tona mahi he e pā ana ki te waru haora.

Excellent taputapu maitai faaore niho, ngaukino, te mamae te rumati. Ka taea e te tarukino atawhai hūhi meinga e te karere entrapment.

Drug "Ksefokam"

ngā tenei raau i roto i te oxicams rōpū. Tenei rōpū o rerekē NSAID nui haere hawhe-ora, hua i roto i te rongo tarukino auroa. Te reira i tino heke te auau o te fariiraa i medicament. Nō reira, heke te mōrea o ngā pānga taha te.

Drug "Ksefokam" Ko o te kaha rawa ki te whakaora i te mamae. Ko tōna pānga analgesic i runga i faaiteraa kaha rite ki te rehunanu. Heoi, pērā i te muri, e kore he faatîtîraa te taputapu, me te kore e pā te pūnaha io pokapū.

I roto i te whakamātautau, i kitea ai e relieves te tarukino mamae mō te 12 haora.

Ko te utu o te raau taero i roto i te puka papa (8 mg) № pikau 10 Ko 205 moni.

Drug "Rofecoxib"

Te raau he analgesic anti-inflammatory, antipyretic me pānga anti-edematous. Whakaritea rawa whai hua mo nga ma'i e whai ake nei:

• periarthritis ma'i;
• kaikōiwi;
• tendonitis;
• bursitis;
• wharanga iohere o tuhonohono e, uaua.

Ko reira rawaka ki tōtika faaore i te tarukino "Rofecoxib" momo o tohu fakamamahi meinga e roro, osteochondrosis, purupiti. Tikanga maitai relieves lumbago, niho tunga, syndrome radicular.

e kore e waiho i raro ki te whakaaetanga i te tūroro ki te huangō te tarukino, i muri i te mamae i te whakaeke ngakau, patunga. Ehara i te mea e tika ana ki te whakamahi i te reira, me te iwi ki te mate oncological, takawhita me atherosclerosis. rāhuitia te tarukino te mō ngā tamariki i raro i 12 tau. I tua atu, i mua i te whakamahi koe i he mea tika ki te āta whakaaro i te pānga taha taea.

Drug "Parecoxib"

Ko te tikanga pai e ai ki te whakaiti i te whakautu inflammatory, me te takoha ki te whakaiti o te tūtohutanga o receptors mamae tenei. Ko te tarukino i roto i te tono mō te tūroro pangia pokanga.

faaore te reira i syndromes mamae o āhua ki te kaha nui. E whakahaeretia ana i muri i hip katoa, me te turi whakakapinga, hysterectomy, coronary pokanga iatuku karo, whakamahia i roto i te mahi niho.

Ko pono takitahi inenga whakaritenga. Tei te reira i runga i te āhuatanga haumanu me te tohu. e kore tamariki i raro i te 18 tau o te rongoā tikanga.

Drug "Arcoxia"

He ingoa tetahi atu te rongoā - "Etorikoksib". huru no te tikanga e antiinflammatory, āhuatanga analgesic tiketike. whakatairanga te faaineineraa inhibition o te hihiko mamae.

Tūroro ki mate o te pūnaha musculoskeletal ki te awhina o tenei taputapu kia whakakahoretia atu o pakeke te ata. Kua pai ake ratou nekeneke tahi, te whakaiti i te kaha o te mumura, maitai manaaki i te mamae. Ki runga ki te fariiraa i te pānga haumanu puta i roto i rua tekau-wha meneti. Kei te pai te whenumi te taonga tarukino kaha i te bloodstream. huru no te faaineineraa e bioavailability teitei. Tenei taupū Ko 100%.

Ka taea te whakaritea te horopeta o te raau anake i te tākuta. Te reira i te tikanga pae i 60 mg ki 120 mg mō ra.

E kore te te tarukino tikanga mo te whakamahi o hapu wahine me ngā tamariki ki runga, ki te 16 tau.

mutunga

e kore e tu ana Pūtaiao Modern tonu. Whanaketanga o hou, NSAIDs whai hua atu. Rārangi o atu atu i te whakatupuranga hou o taero, i runga, ka taea ki a koe te whiriwhiri i te taputapu pai hoki tetahi pathologies. Heoi, kia mōhio e kore e taea e ki te whakaora i te mate i enei raau taero. E ratou anake te pānga anti-inflammatory, me te analgesic.