Makroprolaktin - he aha te mea te reira? Analysis makroprolaktin: täkupu me te ine

Prolactin (lyuteotropnym) huaina te taiaki whakaputaina e te pūtau rapae o mārōrō,. he maha o ngā momo, te puka i roto i te mea te reira i roto i te tangata i te rawa kua. Kei te makroprolaktin Ko tētahi taua puka ira luteotrophic. He aha te mea te reira, he aha e ona mahi me ngā āhuatanga, whakaahuatia i raro nei.

Concepts prolactin

Kei te taiaki o pūmua, me te whakaaro taonga peptide prolaktinpodobnyh. hāngai ana tona taonga i runga i te whai wāhitanga i roto i te tukanga o te uri, me nga okana e he pukupuku o nga mahi - te repe mammary.

Ko te receptors e urupare ki prolactin Kua kitea i roto i te tahi atu wahi o te tinana, engari ko te reira mārama tonu te aro ratou ki te pānga o ngā matū hormonal. E kitea receptors tairongo i roto i te whekau e whai ake nei:

• kōateate;
• marama;
• te thymus;
• ngakau;
• repe taiaki;
• whatukuhu;
• kōpū me ovaries;
• kiri.

vai te taiki i roto i te toto tangata i roto i ngā puka e toru: 85% o te rauemi e te ahua o te waetahi, 10% - puka dimer me 5 anake% kei roto i te puka makroprolaktina.

Ko te mahi o te prolactin

Ko te matua "mahi" o te taiaki ko ki te whakapiki ake i me te mau tonu i te taumata rawaka o te hanganga o te waiu i roto i te whāngai ū. I roto i te hapūtanga, mau tonu te taumata rawaka o te prolactin sex taiki estrogen. I muri whanau te tamaiti ko te nui o te estrogen heke tino.

I roto i tenei wā tonu te hanga o te prolactin e kōmata whakaongaonga o mechanoreceptors. pāngia e ratou ū kōhungahunga kaha te tuku o te oxytocin, e kumea te waiu. Ie prolactin whakaongaonga waiu production me tona haaputuputuraa i roto i te pouaka, engari i roto i te tukanga o te tohatoha waiu tutuki oxytocin.

Ka taea te e ngā kite te mahi o te prolactin i roto i hapūtanga i runga i te whanau hou. nohanga High o taiaki waha Imprint i runga i te tamaiti. He ra torutoru i muri i te whanautanga o aaka o te tamaiti, rawa, ka taea e waiho he rere Academy e kore e rapua e te wawaotanga atu, me te takitahi whakamatauria i roto i te wiki tuatahi o te ora.

Ētahi atu āhuatanga ira luteotrophic:

• inhibition o kano;
• toronga o te wā o te oraraa o te luteum ngä;
• ārai tetahi hapūtanga;
• pānga iti analgesic;
• whai wāhi i roto i te hanganga o te surfactant;
• whakarite kātakí ārai o te kukune;
• whai wāhi i roto i te whakarite orgasm.

Ko te tikanga o te whanaketanga mate

I roto i nga tangata hauora me te wahine kore-hapu nei e kore raruraru hauora, leva prolactin e te taonga dopamine kaha. Kei te synthesized te reira i roto i te hypothalamus. I tetahi tikanga pathologic takahia te hononga i waenganui i te hypothalamus me repe, hua i roto i adenohypophysis pūtau synthesize taiaki luteotrophic me te whakanui ake i ona taumata i roto i te serum.

Makroprolaktin - he aha te mea te reira?

Ko te ahua o te prolactin i he taimaha rāpoi tiketike tenei. vai te reira i roto i te tinana i roto i te moni iti. Ko te taa o te puka - kōrero kaha hormonally taonga immunoglobulin.

kia Prolactin me makroprolaktin i roto i te nui i runga i te täkupu reira anake i roto i te hapu, me te lactating wahine. E whakaaro tahi atu take katoa ki te kia pathological.

Makroprolaktinu he taimaha rāpoi teitei, ahu ki te whakaemi i te tinana. Etahi hanga putanga taiaki luteotrophic tika ki reiti tere o iti taimaha rāpoi.

Makroprolaktin, te tere o e ka e kōrero i raro, kua he mahi koiora iti, a konei, e kore ai huringa iti i roto i tohu tona tinana whakautu. Ko te pikitia haumanu he ngoikore, e haere tahi e raruraru o te huringa paheketanga, e kore te mea nei i te tohu motuhake o te māuiuitanga ranei.

Ko te māngai o te tane e hoki synthesized e tenei taiaki. Ko ia te kawenga mō te hanga o te parāoa, ratou mahi, me te kōtuitui o te testosterone. He nui raro atu i roto i nga wahine whika tangata makroprolaktina.

Anga matou hoki ngā taumata o te ako taiki, me te ona āhuatanga kounga me te ine whakaritea i roto i te take o te pākoko roa take tātaritanga.

Gipermakroprolaktinemiya

Ki te whakaarahia makroprolaktin, ka karangatia e te kāwanatanga taua te gipermakroprolaktinemiey. E kore te mea tenei māuiuitanga he take precipitating i te whanaketanga o te pukupuku mārere o te uma me te osteoporosis rite whakaritea ki te āhua o te whakanui ake i te nui o prolactin noa.

Me mahara te reira e te ara koi i roto i ngā taumata taiki i roto i te whāngai ū-kore ta maumaui i te mahi o te pūnaha hypothalamic-rapae o. Ko te aroaro o tino moni makroprolaktina kia whakaatu rite dysmenorrhea, ētahi wā noa hei te take o te pākoko.

prolaktinoma

Ko te wā "prolaktinoma" e pā ana ki te pukupuku mārire o te rapae o, i te mea he āhuatanga o te hanga ira luteotrophic. Ka taea e Adenomas tupu i roto i rua wahine me te tangata. Ko tonu e kore etiology putanga prolactinoma mārama. He whakaaro o te predisposition tuku, me te te meka e pukupuku puta i roto i whakarara ki te māuiuitanga o te tahi atu whēkau o te pūnaha endocrine.

E rua ngā momo o te pukupuku whakarōpūtia e ratou rahi me te wāhi:

• intrasellyarnye kore whakawhānui tua atu te turcica Tira , a ka whai i te diameter o iti iho i te 10 mm;
• ekstrasellyarnye whakawhānui tua atu te turcica Tira, a ka whai i te diameter nui ake i te 10 mm.

I tua atu ki te syndromes matua me mau faaiteraa, ki i whakaritea nga tohunga ki te tātaritanga me te prolactin makroprolaktin, i reira e he maha o te tahi atu tohu haumanu o te mate:

• whāiti o te parae ataata;
• he heke koi i roto i te acuity ataata;
• wahia i roto i nga kanohi;
• ngoikore ki te whakamahi i kite piringa;
• ānini;
• korekore;
• manukanuka me te kārangirangi;
• i roto i ngā take kino, matapo katoa.

Haunga tātaritanga taiwhanga, ki te hoatu i te tātaritanga tika, te whakamahi o CT ko MRI o te roro, whakamātautau whakaongaonga (hormonal) me densitometry (wheua kiato tata whakamahia mō te pārōnaki).

tātaritanga Āhuatanga

Tātaritanga i runga i makroprolaktin - he aha te mea te reira? Tenei tauhohenga tikanga immunohemilyuminestsentnoy tātaritanga, whakaritea nei ki tūroro katoa ki ngā taumata teitei o te prolactin i te tinana.

Ko te tātaritanga he tetahi o te tikanga auaha. A, no te te pupuri i te reira ki rāpoi taiaki "podselyayut" matūriki antibody e, na roto i te here ki te prolactin turama wahi kitea ki te iraruke hihi-katikati. whanganga te taumata o te luminescence te luminometer - motuhake pūrere kawe.

tohu ine makroprolaktina takoto te whakamahi i polyethylene glycol. whakahaere ratou i te waipara o complexes ārai. Ki te i muri i te tukanga i roto i te serum takoto te iti iho i te 40% o te katoa taumata taiki luteotrophic, he taunakitanga tenei e te tokomaha nui o te makroprolaktina rauemi uiui.

Tuhinga mō te tātaritanga

He he maha o ngā āhuatanga i roto i nei tohunga whakaritea ki etahi tohu kounga, me te ine o te prolactin me ona puka. kawea Tātaritanga i runga i makroprolaktin i roto i te wā e whai ake nei:

• Galactorrhea - secretion rerekē o te waiu, colostrum ranei;
• aroaro prolactin - puku adenohypophysis e synthesize i te nui rawa o te taiaki taonga;
• mate ohorere o te whakakitenga;
• pākoko;
• ngaro o te paheketanga neke atu i te ono marama;
• uterine toto o etiology unknown;
• ako i te māuiuitanga o te rapae o;
• kore auau o te kano;
• osteoporosis;
• uma;
• aromatawai o te whai huatanga o te prolactin therapy.

mahi Norma i roto i wā rerekē

Tau prolactin detectable (hua i roto i mkIE / ml):

• auau toa - 44,5-375;
• täkupu wahine - 59-619;
• postmenopause - 38-430;
• whanautanga tamariki - 205,5-4420.

E te tikanga hua rapunga Makroprolaktina i taua taatou:

• makroprolaktina nui nui;
• makroprolaktin Kua kore tāutuhia;
• he maha nui o feaa makroprolaktina.

hua pai

takoto Gipermakroprolaktinemiya ki te whakamārama o te pathologies e whai ake nei:

• pukupuku hypothalamus;
• tukanga puku hypophysis;
• mate thyroid (heke o secretion hormonal);
• syndrome kura kākano polycystic;
• täkihi;
• mate ate;
• kōhikohiko repe adrenal, iti hoki adrenal ;
• erythematosus lupus pūnahanaha;
• momo kaikōiwi;
• hē pyridoxine huaora.

te tikanga hoki te nui nui o te aroaro makroprolaktina e taea e te manawanui i te wa roa ki te tango i te raau taero rongoā.

Ko te taumata o te mana hormonal:

• antihistamines;
• antipsychotics;
• Diuretics;
• antihypertensives;
• antipsychotics;
• te whakawhānau-waha;
• pōuritanga;
• antiemetic i roto i ngā rahinga nui, me te ki te whakamahi roa.

uara iti

I roto i te tahi mau āhua makroprolaktin, te tere hoki wahine e rerekē i runga i te wā o te ora kia iti iho i te mahi tino pai. Ko āhuatanga o te take e whai ake nei tenei hua:

• infarction rapae o, tupu ki te puipuitua o mate toto nui i roto i whakawhanau;
• perenashivanie hapūtanga (neke atu i te 41-42 wiki);
• whakamahi wā roa-o taero ki te aro haehae, "calcitonin", tikanga hormonal, "rehunanu", "rifampicin", "Nifedipine".

Ko wai e whakaturia ana te ako me te wahi ki te tuku

kia tonoa te ako etahi tohunga: e toketā ki, roma mimi he tafe'anga ranei. haehae Tātaritanga i roto i taiwhanga o haumanu rata motuhake me pokapū whakamahere whānau. e hiahiatia ana hoki te tātaritanga o te toto venous te.

Ko te hua ki te kia tika, me te whakarite i te manawanui mo te makroprolaktin tātari:

1. 12 haora i mua ki te tuku ki te paopao ki te kai.
2. He ra torutoru i mua i te fariiraa e kore whakamahi i taero i runga i te pūtake o estrogens me androgens. Ko te mātanga, nana nei i hoatu te aronga, me e te manawanui e pā ana ki reira.
3. Hoki 24 haora ki te mutu rawa rongoā.
4. Hoki te maha nga ra i mua ki te tātari, ki te whakahaere tikanga i roto i tetahi mahi tinana, me te karo i ngā āhuatanga taumaha.
5. I te ra o te tuku o te tātari e hiahia ana koe ki te mutu kai paipa.

mutunga

Kei te makroprolaktin kotahi puka ira luteotrophic. He aha te mea te reira, he aha e nga āhuatanga o te taki tona kounga me te rahinga - te mōhiohio e tika ana mō te hono i ia e hiahia ana ki te riro te mau metua i roto i te heke mai, kei roto i te tukanga o te whakamahere haputanga ranei.