Hauora, Titiro
Inhibitors anhydrase Carbonic: tikanga o te mahi o te kanohi makaka mo te papahewa
inhibitors anhydrase Carbonic he Diuretics, kahore e nei whakamahia rite Diuretics mochegonki ranei. Tohu hoki enei taero he papahewa. Kia whai whakaaro ano tatou i roto i te kōrero atu i te mea tino rongonui.
Acetazolamide (Acetazolamide)
He āhuatanga diuretic. Mutu anhydrase carbonic tākihi tubules proximal te whakaiti i te reabsorption o K, Na me te wai (diuresis ai he hua), arata'i te reira ki te hekenga i roto i te BCC me acidosis pūkoro. depresses anhydrase Carbonic te tinana ciliary me arata'i ki te tukupu o te pēhanga intraocular, a hoki te whakaiti i te secretion o waikaru i roto i te roro ai mahi antiepileptic. He absorption pai i te wahi gastrointestinal, Cmax i te toto i roto i te rua haora. Pānga taea muri ake ki te 12 haora. 40-60% Whakahekea IOP me te whakaiti i te hanga o te inu intraocular.
Tuhinga & Inenga
Ko nga tohu matua: takawhita ocular, papahewa. I roto i te papahewa, tangohia te roto i 0.125-0.25 g 1-3 wa he ra, ia hoki 5 ra, i muri i nei hiahia te mea kiano i matao e rua-ra.
ngā pānga taha: whakapairuaki, mate o hiahia, korere, mate pāwera, tikanga waimaero o te pa, paraesthesia, tinnitus, te momoe. tenei katoa i taea e tīmata inhibitors anhydrase carbonic. He contraindications hoki teuteu. Tenei te tūtohutanga nui (ki sulfonamides tae), te mate o Addison, ma'unimā ki acidosis, mate ate whakapeka, me te mate tākihi, hapūtanga, mate huka mellitus, uremia.
here Raihana: Embolism pūkahukahu, emphysema pūkahukahu (pea te whakanui ake acidosis).
Te raau: Papa whakaputaina i roto i Poland Polpharma "Diakarb" ki 0.5 g
Dorzolamide (dorzolamide)
Inhibits anhydrase carbonic isoenzyme II ngohe (Whakarewa tauhohenga hydration reversible o te hauhā me te carbonic waikawa maroketanga) ciliary kanohi te tinana. heke secretion makuku intraocular e 50%, pōturi iho te hanganga o ngā ngota hauwai pākawa, a wāhanga whakaiti te waka o te wai, me te konutai. Heke e 38% o te hanga o te inu intraocular e kore e pā i te matamua.
Tuhinga & Inenga
Tuhinga: tuatahi, me te tuarua papahewa tuwhera-koki, takawhita ocular. tohua te raau e 1 te maturuturunga iho 2-3 wā i te ra.
ngā pānga taha: paresthesia, mate taimaha, korekore, rashes kiri, aplasticheskayaanemiya, agranulocytosis, rohirohi, ānini, paitini necrolysis epidermal, reka kawa i roto i te mangai, whakapairuaki, hua i roto i te matotoru o te taupoki io, iridocyclitis, blepharitis, keratitis, pīkaru, photophobia, kite te peroo, te kaikā a mania sensation i roto i te kanohi, hūhi, Stevens - Johnson syndrome, tahu, kanohi waiwai.
Ko te inhibitor anhydrase carbonic (pata kanohi) kua te contraindications e whai ake nei: te tūtohutanga nui (ki sulfonamides tae), tamarikitanga, mate ate whakapeka, me te mate tākihi, te hapūtanga me te ū.
Te faaineineraa: eyedrops "Trusopt" kei roto 1 ml o te 20 mg otinga dorzolamide hydrochloride. oko - 5 ml. Kei te whakaputaina te reira i roto i te Netherlands e Merck Sharp & Dohme.
inhibitors anhydrase Carbonic: Brinzolamide (brinzolamide)
pūārai auaha o te anhydrase carbonic he te kaha, ka tono topically ki whakaiti nui, me te IOP mana. Brinzolamide roaa selectivity tiketike mō te anhydrase carbonic II, me nga āhuatanga ōkiko tino pai ki te tomo tōtika ki te kanohi. A, no te whakaritea ki te dorzolamide me atsetozolamidom kitea reira e brinzolamide - te rōpū taonga tino puai o inhibitors anhydrase carbonic. He he taunakitanga e whakahaere wā rō-uaua ranei o brinzolamide arata'i ki te whakapai ake o te kōpae whatu. A whakaiti reira e te toharite o te 20% IOP. e kore e mahi te reira i te inhibitors anhydrase carbonic katoa. Ko te tikanga o te mahi ahurei i brinzolamide.
Tuhinga ka inenga
Tuhinga: takawhita ocular, tuwhera-koki papahewa. Whakamahia 2 nga wa he ra mo te maturuturunga iho.
pānga taha: reka anuanu, sensation tinana ke, atarua ki runga ki instillation (wā) me te sensation tahunga. Whakawhitia rohe pai atu i dorzolamide.
Contraindications: tūtohutanga nui ki te tarukino (ki sulfonamides tae), o tamariki tau, hapūtanga me te ū.
Te faaineineraa: eyedrops "Azopt" kei roto 1 ml o te whakatārewatanga o te 10 mg brinzolamide. oko Raukaha o 5 ml. I whakaputahia i roto i te USA e Alcon.
He aha atu he inhibitors anhydrase carbonic?
pärönaki prostaglandin
Latanoprost (latanoprost) - receptor prostaglandin agonist whiriwhiri. Whakanuia ai matamua o te wai intraocular roto i te Uvea, e arata'i ki te e tukupu ana o te pēhanga intraocular. Pānga i runga i te hanga o te waikaru kore e te āwhina. E taea te huri i te rahi o te tauira, engari paku anake. A, no te backfilling te ô i roto i te puka o te isopropyl Etera i roto i te taupoki io me i reira hydrolyzed ki te āhua o te waikawa kaha biologically, e taea te tautuhi i te 4 haora tuatahi i roto i te inu intraocular me i wē i roto i te haora tuatahi. 0,16l / kg - rōrahi o tohatoha. E rua haora i muri i tua tutuki te kukū rawa i roto i te katakata wai, i muri nei te tohaina ai ki te timatanga o te wāhanga mua, i.e. nga kamo, me te kirikamo, a ka tomo ki te wāhanga posterior (i roto i te moni iti). Ko te puka kaha i roto i te kopa o te kanohi e kore ngā te metabolized, te nuinga i roto i te biotransformation ate. Pai io, kua excreted metabolites i roto i te mimi. Kia titiro a ki etahi o nga inhibitors anhydrase carbonic.
Unoprostone (unoprostone)
unoprostone Isopropyl Ko te pärönaki o te docosanoid tere whakaiti pēhanga intraocular (IOP) te whakamahi i te huarahi pharmacologic hou. Te kore te huri i te hanga wa o te inu intraocular, whakahaere tona matamua. Kua whakaaturia Studies e, whakaritea ki 0.5% maleate timolol, unoprostone isopropyl he mahi rite noa pai ranei ki te whakaiti IOP. E kore e te tarukino pā te whare noho, me te kore e meinga whakaiti o te rere toto i roto i te kopa ocular, miosis mydriasis ranei; e kore ano e whakaroa houtanga Corneal kitea. I muri wā unoprostone isotropy tonu kihai i kitea i roto i te wē.
kia whakaritea inhibitors anhydrase carbonic mō te papahewa anake i te tākuta, e kore e whakaaetia rongoā-whaiaro.
Similar articles
Trending Now