CA-125 täkupu. He aha e whakanui i te reira?

Ko mate pukupuku ovarian te take tuatahi ārahi o matenga wahine i pukupuku mārere. Raraunga whiwhi e te International Agency mō Rangahau i runga i te Cancer, fokotu'u e te ao ia tau, mate e pā ana ki 165 000 take o te mate pukupuku ovarian me e pā ana ki te 100,000 wahine i tenei mate. I roto i Russia, 100 mano wahine whakaaro, mō te 16 take me 8 mate i te hape o te pukupuku ovarian mārere. Life tümanako ki tenei mate ko te mōrahi o te 5 tau, me o e pā ana ki te 30% enei o take, rite tahuri te nuinga o nga wahine ki tākuta mō te awhina anake i roto i te wāhanga whakamutunga o te mate, ka mana'o te reira tino mate.

Ko te whanaketanga o ngā tikanga whai hua o te tātaritanga o tenei momo o te mate pukupuku , ko te mahi akiaki. I tēnei wā, i reira e maha tikanga rerekē o te tātaritanga: ultrasound, X-ray tomography me te kōwarotanga autō, immunological me tätari matüora, laparoscopy. Ko te tino noa, me te whānui whakamahia mō te whakatau i te aroaro o te mate pukupuku ovarian - glycoprotein antigen CA-125, ara ko reira te matua oncomarker tenei momo o te mate pukupuku. CA-125 Normal toto 35 U / ml.

Ko reira i roto i te endometrium tonu te nui iti o CA-125 i roto i nga wahine - te mucosa uterine. Nā ki te aroaro o ngā tauārai māori, e kore e taea e tomo ki roto ki te bloodstream. CA-125 taumata e whangai ana ki te ara ki te 35 U / ml, engari i roto i paheke anake, me te maha ki endometriosis.

auau CA125 Ko 35 U / ml ka kore he tohu nui i runga i nga take i runga, he mea he tohumate o te mate pukupuku.

Tenei i taea e kia mate pukupuku:
- te kōpū, korere kākano, ovaries
- uma
- te marama
- repe taiaki
- pūnaha kūnatu (kopirua, ate, puku)
- te tahi atu malignancies.

Ka taea te nui haere tirotiro o CA-125 glycoprotein kore anake i roto i te take o te wahine mate pukupuku pūnaha whakaputa uri, kia hanga i te tātaritanga hāngai anake i runga i enei raraunga, e kore e taea, me te he. E hiahiatia ana akoranga atu i roto i tenei take. Ko, e kore ai te tātari o CA-125 hei te tohu tātaritanga anake.

Hoki e taea e auau CA125 ara feunga kaha i roto i te aroaro o te pukupuku gynecological Koló mate inflammatory o te konga ranei. Paku nui haere tohu puku i roto i te tikanga hauora e whai ake nei:
• cysts ovarian
• Endometriosis
• mumura o te konga
• paheke
• Peritonitis
• kiripūkahu
• STIs (paipai mate e)
• Hepatitis, cirrhosis
• Pancreatitis i roto i te puka ma'i
• ano, i reira he take o etahi hua i roto i CA-125 puku tohu i roto i mate autoimmune me i te huatū tuatahi o te hapūtanga.

Toto tohu Rangahau CA-125 te nuinga whakamahia ki te whakatau mate pukupuku ovarian serous, ka whakatau i tona hohokitanga. I roto i te tata 83% o te tūroro ki te wahine mate pukupuku ovarian te taumata o tona ihirangi ko e pā ana ki 123-164 U / ml i roto i te toto. Hoki ovarian puka mate pukupuku whārahinga CA-125 paerewa serous tei runga i puku atamira ano: ko te mahi tuatahi, me te tuarua, ko te hua i roto i CA-125 i roto i pā ana ki 50% o te wā, he kua toru me te wha hikoinga i roto i tūroro katoa. I roto i nga wahine ki te ascites mate pukupuku ovarian puka täkupu CA-125 i roto i te toto nui -20 ki te 10 mano. U / ml.
Ki te tango pai o te puku ki te hahau ranei tohu hāparapara ihirangi i roto i te toto CA-125 heke. Ki te nui haere atu CA-125, ko reira he tohu o te ahunga whakamua o te mate pukupuku. Tikanga, ki te aromatawai i te whai huatanga o te hahau CA-125 taumata e ako rite te aroaro o ia akoranga o te maimoatanga me te i muri i tona otinga. Ko te periodicity Ko 1-2 marama.