"Zanidip": tohutohu mō te whakamahi, tūroro tūturu me rata ritenga. "Zanidip-Rekordati": aratohu, arotake, analogs

E ai ki ngā tatauranga, e pā ana ki 26% o ngā pakeke i roto i te ao mamae i te pēhanga toto tiketike wā. Nuinga o ngā wā e pā ana tenei mate te ki te predisposition ira. Heoi, i reira he take atu mo tona takanga. Ko ētahi o ēnei mōmona, paowa, rōpū nui o te tote, te kore o ngā āhuatanga wahi me huaora i roto i te tinana, te tūkino waipiro, te ahotea, iti mahi tinana, me etahi atu.

Me mahara hoki käore te reira e te whanaketanga o te takawhita tei runga i tau o te tangata. Ko te tuakana ko ia, te teitei te mōrea o te taua kāwanatanga pathological. I te tau o 40 tau, ko tata tonu te mate te hua o pāpaka iaia sclerotic.

mōhiohio whānui

Nuinga o ngā wā, hoatu kaiwhakaako ratou tūroro te tātaritanga "takawhita faufaa". He aha te mea te reira? Ko te mate ma'i, me te ahua o te takawhita. Tona tohumate haumanu matua mahi tairanga tamau me te roa o te pēhanga toto.

kia rerekē huringa i taua mate. Heoi, ratou matua ana ki oko toto, me te ngakau.

I roto i te tikanga ki te whakapai ake i te huru o te manawanui, tūtohu tākuta tenei tarukino rite "Zanidip". ka arotake o tūroro i runga i te whai huatanga o te tarukino kia kōrero i roto i te rauemi o tenei tuhinga. Ano ka kitea e koe i reira ngā mōhiohio i runga i te āhua o ki te riro mea rongoā, ki te i ia tetahi analogues me ngā pānga taha.

Whakaahuatanga, hanganga, te āhua me te tākai

Kei te rongoa te medicament "Zanidip" ako i roto i te paihere pepa e tukua i roto i te puka o papa marama puka kōwhai me te a tawhio noa, me te biconvex he tohu i runga i tetahi o nga taha. He kiriata-Uwhi ratou me te whai i te kauruku kowhai i runga i te mea kiano i matao.

Ko te whakauru kaha o tenei tarukino mahi lercanidipine hydrochloride. Hoki, ngā reira me wāhanga pŭpŭ tauturu, e kua faahoho'ahia rite povidone K30, monohydrate reihuka, te konutai carboxymethyl māngaro, microcrystalline cellulose me stearate konupora.

Ki te whakaaro ki te kiriata-paninga waihanga, ka kua tito reira o matū pērā i Opadry Kōwhai, talc, hypromellose, Titanium hāorarua, rino waikura tae kōwhai me te macrogol 6000.

Hokona ai e "Zanidip" pire i roto i te mōkihi namunamu, e kua whakanohoia i roto i ngā pouaka pepa.

āhuatanga pharmacological o taero

I mohio koe e ko te tarukino "Zanidip"? Tohutohu i runga i te tono tohu e ko te reira i te hongere pūārai konupūmā puhoi. Ko tōna whakauru kaha ko te ranunga racemic o nga stereoisomers dextro-a levorotatory. Me mahara hoki käore te reira e ko te reira i te pärönaki o 1,4-dihydropyridine.

Tenei medicament tīpakongia ārai nāianei o katote konupūmā ki ngā pūtau cardiac, ngā pūtau iaia me te uaua maeneene.

Ko te parau tumu o te pānga antihypertensive pūmau o te tarukino he tika ki te pānga relaxant tika i runga i iaia ngā pūtau uaua maeneene.

E ai ki nga tohutohu, i muri i te fariiraa i te pānga haumanu o te medicament tutuki te i muri i 5-7 haora. tonu te roanga o tona mana kua puta noa te ra.

Nā ki te selectivity tiketike o te tarukino ki te iaia ngā pūtau uaua maeneene, e kore e whai te reira i te pānga kino inotropic.

Na he aha te mea he tarukino "Zanidip-Rekordati"? kī Guide e ko te reira metabolically rongoa kūpapa e kore e whai nui mana i runga i te ihirangi o apolipoproteins me lipoproteins i roto i serum toto, me te e kore e huri i te kōtaha o te ngako i roto i te iwi ki te takawhita.

Ko te kinetics o te tarukino

Hea whenumi tarukino "Zanidip"? Ka whakamōhio ngā tohutohu mō te whakamahi ia tatou e i muri i te fariiraa i te papa (10 ranei 20 mg) roto lercanidipine tata rawa whenumi i te wahi gastrointestinal. I muri 1.5-3 haora te kukū mōrahi o te tarukino i roto i te wē toto tae te uara o 3.3 ng / ml 7,66 ng / mL aua ranei.

Ko te tohatoha o te raau taero i roto i te kopa, me okana e tino hohoro wahi. Communication ki pūmua wē nui 98%. kitea papa horopeta toutou o ratou whakaeminga te.

kawea te pākia o te tarukino i roto i roto i te haere tuatahi i roto i te ate. puta tenei i te biotransformation CYP3A4. hanga tenei he maha o metabolites e kahore mahi pharmacological.

rongoā whakaaturia "Zanidip", arotake o nei e te aroaro paku raro i roto i nga whekau, me nga whatukuhu. E rua ngā wāhanga tango o lercanidipine: wawe nei wā ko 2-5 haora, me te whakamutunga - 8-10 haora.

Ko te tarukino tonu e kore e whakaritea e kitea i roto i te feces me mimi.

Iwi ki te ate tākihi ihirangi mate pūmua o te wē ranei kei te tino heke. I roto i tenei whakaaro, kia nui nui haere te hautanga noa o te taonga kaha o te medicament.

Tuhinga ki te farii i rongoā

He aha whakaaro e taea te whakaritea rongoā "Zanidip"? korerotia Reviews o rata e whai hua whakaaturia tenei kaihoko ano i roto i takawhita faufaa, me te ngawari ki te whakaōrite pakeke.

Contraindications ki te farii i te papa

E ai ki nga tohutohu, te tarukino "Zanidip" e kore e tika kia tangohia i raro i nga tikanga e whai ake nei:

• mahi ate nui;
• āhua kore ngakau ma'i (rawa decompensation taahiraa);
• waimaero mahi tākihi;
• angina iu ;
• i ngā ki inhibitors kaha isoenzyme CYP3A4 (hei tauira, "ketoconazole", "erythromycins", "itraconazole") me ki "cyclosporin" me te hua hīmoemoe wai;
• i roto i te hapū;
• arai o nga oko toto e haere mai i te roro maui o te ngakau;
• reihuka, hapa lactase me malabsorption syndrome galactose / kūhuka;
• i roto i te whāngai ū;
• tata i te infarction myocardial (i roto i te wā o te kotahi marama);
• Women o te whanautanga tamariki tau e kore e nei te whakamahi i te tikanga pono o te ārai;
• i raro i tau (miramira me te haumaru kihai i i whakapumautia);
• hypersensitivity ki lercanidipine me ētahi atu pārōnaki dihydropyridine tetahi wāhanga o te rongoā ranei.

rongoā tango tūpato

tūtohutia te medicament "Zanidip-Rekordati" tūpato te ki te tango i te iwi ki te mahi waimaero ate (āhua, me te ngawari), ma'i nedostatochnostyusindromom pakohu ngakau, kore ventricular maui , me te mate te AVC, a ki te fariiraa tukutahi "Digoxin" beta-blockers.

Papa "Zanidip": tohutohu mō te whakamahi

I roto i te tirohanga o te tau nui o ngā aituä me whakahaere raau whakaaro e kaimahi mātanga. Tikanga, tūtohutia te tarukino kaha te ki te tango i roto i te nui o 10 mg kotahi te ra.

kia kawea pire i roto i te ata, hoki ¼ haora i mua i te parakuihi.

Tei runga i te pānga haumanu o te inenga o te raau taero i raro i whakaaro e taea te rererua, i.e. ki pā ana ki 20 mg. kia puta te whakanui ake pota o medicament āta. Ki te hiahiatia, te hua i roto i te nui o medicament kawea i muri i te rua wiki i muri i tomokanga o te therapy.

Me pēhea e tango ahau "Zanidip-Rekordati"? Kaua e tararua te papa. Ratou te tikanga horomia a horoi ki te nui rawaka o te wai ki raro.

I roto i te paari e hiahiatia No whakarerekētanga inenga te. Otira ka tango rongoā mo ratou huru titau aroturuki auau.

I roto i te aroaro o te kore ate täkihi ranei āhua ako pakeke inenga ranei e kore e hiahiatia. I roto i te torutoru ra tuatahi o te tarukino faaterehia i roto i te nui o te 10 mg, a ka ki te tūpato te whakanui ake i te horopeta ki te 20 mg ia ra.

Ki te te kaha te whakaputa te pānga antihypertensive, heke te inenga i tohua te.

pānga taha

Ka taea e meinga tauhohe e hiahiatia "Zanidip-Rekordati"? arotake Kiritaki e e te tikanga te rōpū o tenei ratou maha puta pānga taha. He aha rite, whakaaro tatou tika inaianei:

• pūnaha ārai: hypersensitivity.
• pūnaha Cardiovascular: tachycardia, angina, palpitations, ngenge;, Makere ki te kiri mata, te mamae pouaka, tohua whakaiti i roto i te pēhanga toto, whakaeke ngakau.
• pūnaha io: somnolence, ānini, whanoke.
• wahi kūnatu: ruaki, dyspepsia, whakapairuaki, hua reversible i roto i whākōkī ate, korere, me te mamae puku.
• He kiri e hikaka te.
• pūnaha musculoskeletal: myalgia.
• Mimi: polyuria.
• Ētahi atu: edema piringa, rohirohi, hyperplasia gingival, rohirohi.

Tohu o te tuwhena rawa

He aha ngā pānga ka whai, ki te tango koe i pota teitei o te tarukino "Zanidip"? Guide ngā nga tohu e whai ake nei o te tuwhena rawa: infarction myocardial, tachycardia pūpū, vasodilation piringa ki hekenga i tohua i roto i te pēhanga toto, he hua i roto i te roanga me te auau o whakaeke angina.

Hei whakakore i taua āhua maimoatanga symptomatic.

taunekeneke tarukino

He reira taea ki te ngā i te tahi atu raau taero rongoā "Zanidip"? Tohutohu mō te whakamahi tohu e riria te taputapu e ki ngā ki inhibitors taua CYP3A4 (cytochrome P450 o te ate), rite "Itraconazole" "ketoconazole" me "erythromycin". Ko e tika ana ki te meka e whakanui i enei rongoa katoa te kukū o lercanidipine i te toto, me te mata, ki te pānga antihypertensive tenei.

tikanga pūrongo fariiraa tukutahi ki "cyclosporin" te contraindicated, rite kia arahi ai ki te hua i roto i te ihirangi o ngā matū e rua i roto i te toto o te manawanui.

rāhuitia Lercanidipine te ki te whakamahi tahi i te hua hīmoemoe wai. kia hua tenei huinga i roto i te potentiation o te pānga antihypertensive o lercanidipine me inhibition o pākia.

kia faaohipa te reira i te tūpato tino i te fariiraa i "Zanidipa" ki taua raau taero rite "Astemizole", "Terfenadine" me "quinidine", me hoki antiarrhythmics o te toru o nga piha haapiiraa (hei tauira, "Amiodarone").

Ko te huinga o te medicament whakaaro ki taero anticonvulsant ( "phenytoin," Carbamazepine ") me" rifamycins "kia whai wāhi ki te whakaiti i roto i ngā taumata toto o lercanidipine, hua i roto i te heke o te pānga antihypertensive o lercanidipine.

A, no te tonu kia aroturuki te huinga tarukino ki "Digoxin" tohu o te haurangi.

maimoatanga tukutahi ki te medicament "midazolam" i roto i te pakeketanga kia whakapiki ake i te absorbability o lercanidipine me whakaiti i tona tere absorption.

Tohunga mea e "metoprolol" Ko te ahei o te whakaiti bioavailability o lercanidipine 50%. I roto i tenei take, e noho tonu te bioavailability o "Metoprolol". E hua ana tēnei pānga i te hekenga i roto i te rere toto ate meinga e beta-blockers.

Te faaineineraa "Cimetidine" i roto i te inenga o te 800 mg ia ra e kore e hua i roto i ngā tino whakarerekētanga i roto i te kukū toto o lercanidipine. Otiia i tona fariiraa titau tūpato motuhake, mai kia whakapiki ake i pota tiketike te bioavailability o lercanidipine me reira ake i tona pānga antihypertensive.

Ki te huinga o "Zanidipa" ki "Simvastatin" te tarukino tuatahi ki te kia mau i roto i te ata, me te tuarua - i roto i te ahiahi.

Ko te medicament "fluoxetine" e kore pānga i runga i nga kinetics o lercanidipine.

fariiraa tukutahi "Zanidipa" ki "warfarin" kihai i pā i te pharmacokinetics o te muri.

O taea te ngā i te moni ki Diuretics, beta-blockers me inhibitors ACE.

kia mōhio hoki tatou e te waihā whakarei ake te lekarnidipina pānga antihypertensive.

tūtohutanga motuhake

Drug "Zanidip", analogues o nei e rārangi ana i raro, kia ki te tūpato tino i roto i te iwi ki te mahi tākihi waimaero me mate te AVC, pera i roto i tenei take, i reira te mea he mōrearea nui o nui haere auau o whakaeke angina.

I mua ki te fariiraa i te tarukino kia tonu kia utua kore ngakau he natula ma'i.

kia kitea ngā tūpato i te timatanga o te therapy, rawa i roto i tūroro ki tohu āhua, me te ngawari o te iti hoki ate.

I roto i te maimoatanga, he reira e minaminatia ki te āta kawe i roto i te mahi e titau tokanga makehe, tae atu i roto i te whakahaere ara. Ko e tika ana ki te meka e i te timatanga o te therapy me i pota te taikaha reira ko te mōrea o te takanga o ānini, te momoe me te whanoke tenei.

tikanga rokiroki, te ora papa o te faaineineraa, me te hoko

Hea e taea te hoko e ahau pire "Zanidip-Rekordati"? Analogs o nga moni ia rongoā hokona i roto i tetahi whare kēmihi. Heoi, e taea te hokona ratou anake i runga i whakahaunga o tākuta.

Kia mau ki tenei rongoā i roto o te taea e minaminatia mō ngā tamariki taitamariki te wahi e kore e te pāmahana nui 30 nekehanga.

Ko te ora papa o te tarukino i raro i whakaaro ko te toru tau. I muri i tenei wā, rāhuitia tango rongoā te.

analogues tarukino

E mōhio o te aha koe e taea e whakakapi pire "Zanidip" koe? Ko te tino uaua ki te kitea analogues o tenei taputapu. pūrongo Tohunga e āhuatanga rite, me te mahi o taua teuteu riro rite "Lerkamen" me "Lercanidipine". Ka mau enei rongoa kia anake kia mō tohutohu hauora.

Drug "Zanidip": arotake o tūroro me ngaio

Ko reira tino whai hua kaihoko antihypertensive. Ko ngā tenei tirohanga e tākuta maha. whakaae tatou ki a ratou, a tata katoa tūroro tango pire "Zanidip". titau ratou e i muri i tango i te rongoā ratou huru mārika i pai ake. Tohu o te takawhita faufaa ko waiho pakeke ngawari me te āhua tata tonu.

Ko te drawback anake o tenei rongoā ko e tango i te reira rawa maha ai ngā pānga taha, rawa i runga i te wahi o te wahi kūnatu me te pūnaha Cardiovascular.

Me mahara hoki käore te reira e maha iwi amuamu e pā ana ki te utu o te tarukino he tiketike rawa. Ko tenei raau i roto i te nui o 28 papa taea te hokona hoki 450-500 moni. Me kï reira i mea ai e kore e ngawari te nga analogues o medicament mea i roto i te puka o "Lerkamena" me "lercanidipine". Ka taea te hokona ratou mo te utu ano.

Tohunga mea e te utu o "Zanidip" tarukino antihypertensive tino ü ana ki tona kounga. E whakaatu ana te reira i tata te katoa o tona wheako roa i roto i te tono.