"Dopamine" - he aha te e? "Dopamine": ako, tono, utu

rite te paura, tioata o te tae ma ki te kakara e papaki ana rangona te tarukino "dopamine" titiro o te waikawa pūmāota. Tenei puka kua reira i roto i te puka o te hydrochloride. "Dopamine" - he taonga wairewa i roto i te wai, me te waipiro. Kei te pāngia te reira e te kawakore, ngā māngai oxidizing me tai rino. Tuhinga ka contraindications ki te whakamahi o te tarukino "dopamine", te ako i runga i tona whakamahi e whakanohoia i roto i ta tatou mau papai.

Tikanga tukuna rite otinga e whaowhia kareti.

āhuatanga pharmacological

"Dopamine" - he taonga, he neurotransmitter. I runga i nga āhuatanga pūkoro tinana o te dopamine ko te kawainga o te Adrenaline me noradrenaline. pānga te tarukino te receptors hāngai, me i roto i nohanga tiketike whakarei mahi α- me β-adrenoceptors. hāngai "dopamine" mahi i:

• whakareinga o te ātete iaia piringa;
• ake i roto i te pēhanga toto systolic;
• whakaongaonga o auau ngakau;
• nui haere putanga cardiac;
• huringa iti i roto i te auau ngakau;
• supply hāora nui.

"Dopamine" whakarei ake hoki te rere toto i roto i te oko o te roro, ngakau, whatukuhu, me paru. Nui ake auau filtration glomerular me te konutai excretion i te tākihi.

"Dopamine" - he tarukino nohopuku-mahi. I muri 5-10 meneti i muri i / mahi v whaowhia mutu. Ko te hawhe-ora - āhua rua meneti. Hawhe o te taonga pāhekoheko ki te pūmua i roto i te wē toto. haere te raau tukanga pākia tere i roto i te whatukuhu, ate me te toto wē tika ki te mana o Mao me catechol-e-methyltransferase ki te āhua o metabolites hohekore me te mātātoa whakaputaina e te tākihi. Kei te tahuri te hauwhā o te whakamahi o te horopeta ki norepinephrine i roto i te tupu io adrenergic. Nā ki te whakakorenga kaha kore ko te haaputuputuraa o te raau taero i roto i te tinana tangata, ara i muri i te wa roa o te fariiraa.

"Dopamine": tono

Tuhinga mō te tangohanga:

• momo Various o te ru, pērā i te pāmamae, cardiogenic, postoperative, hypovolemic, endotoxin.
• iaia whakapeka me kore ngakau.
• Iti putanga cardiac.

"Dopamine" ki ru cardiogenic hiahia motuhake, e faarahi te reira myocardial contractile mahi.

whakahaere te tarukino te pâmuhia. 125 400 ranei ml o rima ōrau otinga o te konutai pūhaumāota otinga kūhuka e hiahiatia ana i te 25 200 ranei mg aua ranei. Ko te kupu, 1 ml o te otinga i whiwhi 200 500 ranei taonga .mu.g. Ki te kore e taea te whakahaere i te manawanui e taea te hanga buka nui o te wai otinga atu takiwa, kia 1 ml o 800 micrograms ko "dopamine". Ki te mahi i tenei, tango 200 mg ia 250 ml o otinga. Ko te tere o te whakataki tae 1-4 UG / kg ia meneti ki te taimaha tinana toharite o 70 kg (2 ki te 11 pata o 0.05% otinga ranei i 1.5 ki te 6 pata o 0.08% otinga). Ko te inenga whakaora - i 5 ki te 9 mg / kg i roto i te 1 min. Inenga "dopamine" 10-15 .mu.g / kg ia meneti he whai hua i roto i te vasodilation me hypotension. Ka taea te nui haere te auau whakahaere ki te 18 .mu.g / kg ia meneti. Ko te whaowhia e wahi, kahore arumanga, me e hipokina te wā i 2-3 haora ki 1-4 ra roa ranei. Ko te horopeta ia ra e kore rawa 800 mg. Ki te introduction o "dopamine" tū te ECG aroturuki. Kei te rite faaotiraa o te horopeta me tere o te whakahaere pēhanga matua, auau ngakau, putanga cardiac, auau ngakau me te diuresis. Ki te kore kore e whakatika hypotension, a heke putanga mimi, kia heke te horopeta.

contraindications

contraindicated te raau i roto i te hui o te raruraru pērā i:

• arrhythmia;
• pheochromocytoma;
• hypertrophy prostatic;
• papahewa katinga.

pānga taha

Ko te kupu whakataki o te taonga i roto i pota nui, he taumata tiketike o "dopamine" Ka taea e meinga pānga taha, tae atu ki:

• faaati;
• tachycardia;
• vasospasm;
• arrhythmia;
• takahi o te manawataki romahā;
• anginal me te ānini;
• whakamātau tinana mamae ;
• atu mau faaiteraa mahi Adrenomimeticalkie.

Mai te mea kaha te whakakorenga o "dopamine", ngaro nga tohu i runga ake ki te raro i te horopeta ranei mutu whakahaere o te tarukino. Ki te pakaru te manawataki te, ko reira e tika ana ki te whakamahi i taero antiarrhythmic, tae atu "Verapamil", "lidocaine" me etahi atu. Extravasation otinga "dopamine" taea arahi ki necrosis o te kiko adipose subcutaneous me o te kiri.

Ara

"Dopamine" i roto i hapūtanga kia whakaritea ai anake, no te maimoatanga tino tika mo te whaea, a ka he ki runga ake i te mōrea ki te kukune te pānga haumanu.

kia whai i te kakano mārama otinga hou me te hapa hue no rapae.

maimoatanga tukutahi ki ētahi atu taero

kia te tarukino kia tangohia i roto i te whakarara ki te glycosides cardiac me Diuretics (hei tauira, furosemide me ētahi atu). ru Hypovolemic titau te introduction o "dopamine" me te toto, wē wē ranei whakakapi katoa.

Kaua e tangohia "dopamine" i te wa ano ki "cyclopropane", inhibitors Mao me māngai mō te rehunga ki āwheo ( "Halothane" me ētahi atu).

waihanga ranunga moata Kāore ki rongoā kawakore o te tahi atu raau taero.

"Dopamine" - he rongoā e whakamahia e te anake i runga i whakahaunga. tei Ko tōna utu i runga i te inenga me te maha o ampoules i roto i te mōkihi, mai i 80 ki te 300 moni ia mōkihi (5-10 ampoules).