"Disulfiram": arotake. "Disulfiram": whakaahuatanga, utu

I roto i tenei tuhinga, faaoti matou ki te korero ki a koutou e te mea he tarukino rite "Disulfiram" tenei. Ka hoki kia whakaahuatia tohutohu mō te whakamahi, urupare me tohu o nga moni i raro. I tua atu, ka ako koe i te mea ko te utu o mea rongoā, kua whakaputaina reira i roto i tetahi puka ngā e kei roto i tona hanganga, a na i runga i. D.

Ko te puka me te hanganga o te tākainga

Ko te medicament "Disulfiram", tohutohu hoki te whakamahi kopakia ana e te i roto i te pouaka i hanga o te pepa, kua hokohoko i roto i te puka o te otinga hinuhinu me papa mo te whakahaere-waha, me te implantation.

whakaputaina te puka tuatahi i roto i oko o te 20 ml, me te tuarua, me te tuatoru - i roto i te oko karaihe i 10 me 20 wae aua.

Ko te whakauru mātātoa o te medicament he disulfiram. Haunga reira, kei hoki te tarukino wae atu (i runga i te puka tuku rānei): pūhaumāota konutai, mannitol, māngaro, te konutai stearate, titi-6000, MCC, konupūmā diphosphate, cellulose hydroxypropyl, waikawa nenehake me te polyoxyl 40.

āhuatanga pharmacological

He aha te mea tatou i mua i rongoa? He aha e mea ratou arotake rata e pā ana ki a ia? "Disulfiram" kua he pānga anti-waipiro korerotia.

A, no te riro koe tuhia tenei taputapu te mo tona pānga nui i runga i te waipiro pākia. Ka rite ki te hua, e hanga e metabolites haumaru, e whakanui i te kukū o ngā matū paitini pērā i acetaldehyde. Ko ia te tangata e whakatau te miramira o te tarukino.

Ki te whakahaere rō-uaua o te medicament, me te ona tūroro waha timata tata tonu ki te ite flushes wera, dyspepsia whakapeka, tachycardia, asthenia kaha, me te ara hypotension whakawehi. I tua atu, i te ahua o te haurangi e acetaldehyde whai wāhi whakakonekone ki waipiro me te whakakorenga o te akina manawanui ki te waipiro.

tawhā pharmacokinetic

He aha te whakaaro kua te tarukino tawhā neke? He aha e pā ana ki ona arotake pūrongo absorption? "Disulfiram" tino tere, me te tata rawa whenumi i te punuatuna.

A, no te whakamahi i te reira, i reira te mea he pākia tiketike o te wae kaha, i roto i nei i hanga e rave rahi metabolites. kawea te takenga o te hua kei te roto i roto i te pūkahukahu me whatukuhu.

Tuhinga

Drug "Disulfiram", te utu o nei whakaaturia te raro nei, tohua te hoki:

• maimoatanga o te waipiro ma'i;
• ārai o matahoki i te maimoatanga o te waipiro ma'i.

Tangohia tenei rongoā i tona houhou ngarahu pai. Me whakarite te reira i te tākuta.

contraindications

Drug "Disulfiram" pâmuhia me waha e kore e tūtohutia hoki te mate e whai ake nei:

• mate neuropsychiatric;
• haurangi;
• mate huka.

Ano, e kore e tenei tarukino tohua i roto i te hapū, te tūtohutanga ki te wae hohe me te wāhanga atu, ū.

kia mōhio hoki tatou e ki te tūpato tino tūtohutia tenei tarukino te ki te tango i roto i te tūroro ki te mahi ate waimaero, pūnaha romahā me te whatukuhu.

Drug "Disulfiram": tohutohu mō te whakamahi

Ko te whakamahi o tetahi ahua o nga moni e whakaaetia anake i runga i whakahau a tākuta. takoto ana te tākuta kei te ki te whakahaere i te whakamātautau ki tonu o te manawanui, a ka whiriwhiri i te talena maimoatanga takitahi, me te horopeta hoki ia.

E ai ki nga tohutohu, te horopeta toharite o te tarukino hoki whakahaere waha ko e pā ana ki 125-500 mg.

Ko te werohanga me implantation o te raau taero, ka kia kia whakamana e te kaitoi mātau enei ngā tukanga. I roto i tenei take i te inenga tūtohutia o te raau taero tei runga i te āhuatanga o te manawanui, me te pakeke o te mate ngā.

pānga taha

ngā pānga taha o te tarukino i roto i te pātai ahau e taea te karanga? He aha e pā ana ki tenei mea te arotake? "Disulfiram" uaua riro take tauhohe taha kino. A, no te ingested kia ai taua mea etahi ine i roto i te wahi kūnatu me te aroaro o te reka konganuku me te whanaketanga o te kakā.

I tua atu, ka taea e maumaui tupu i roto i te mahi io. āhuatanga houhou taua ngā polyneuritis o wahi o raro, disorders hinengaro, mate mahara, disorientation me te ānini.

Ano, e kore e tutakina i te whanaketanga o ngā tauhohe mate pāwera, i rongo nei i te mana o te waipiro (hei tauira, tiango, whiu, arrhythmias cardiac, edema kaka me te infarction myocardial).

Tohu o te tuwhena rawa

Te faaineineraa "Disulfiram" i pota teitei taea meinga pānga pērā i tiango, coma me mōrearea tauhohe neurological.

Hei whakakore i kia noho enei tohu therapy symptomatic i roto i te fare ma'i, e me tika ngā mahi detoxification.

Antidotes medicament

Kua whakamatauria tohunga e kore e taea te whakaaro te neutralization oti o te tarukino.

Ki te tika, kawea te putanga "Disulfiram" i te tinana tangata (horopeta hei tauira, i roto i tauhohe kino ki hou tangohia o waipiro) i roto i etahi ngā tukanga.

Ka rite ki te raau ki tenei whakamahi tarukino waikawa ascorbic. Kei te whakahaerea te reira e pâmuhia. e kore e tenei huānga tukua waipiro ki kia puta ki acetaldehyde, e, i roto i te meka, ai hūhi.

kia hoki kia ratou ephedrine whakamahia me H1-blockers.

taunekeneke tarukino

He mea e manakohia ana ki te whakamahi i ētahi atu raau taero i mua ia tatou rongoa? He aha e pā ana ki ngā taunekeneke tarukino mea arotake? "Disulfiram" i roto i ngā ki anticoagulants faarahi ratou mahi, a ka whakanuia ana hoki te mōrea o te toto.

maimoatanga tukutahi ki rongoā tarukino metabolized nei i roto i te ate, e taea tino haafaufaa i roto i te tukanga.

Te whakakotahi i Mao inhibitors, pōuritanga tricyclic me pārōnaki phenothiazine ki "Disulfiram" whai wāhi ai ki te putanga o tauhohe taha matatini.

Ko te huinga o tenei tikanga ki "buspirone" ai te whanaketanga o horihori. rongoā pērā i "Amitriptyline", maha whakarei ake te pānga o "Disulfiram" me whakaara ake ona pānga paitini i runga i te pūnaha io.

I Tirohia medicament ahei o te whakanui ake i te kukū o te chlordiazepoxide me diazepam i roto i te toto, te whakaiti i te kaha o tauhohe paitini, me te meinga whanoke.

Ki te huinga o "Disulfiram" ki "isoniazid" kia whakawhanake whārua me whanoke, "metronidazole" - whakama me te āhotea whakapeka, he "Omeprazole" - waimaero mahara, me kawhe - heke tona excretion i te tinana.

"Chlorzoxazone" faarahi te kukū o anti-waipiro tarukino i roto i te toto, a "Chlorpromazine" faarahi ho'ii hypotension.

Drug "Disulfiram": arotake, utu me analogues

pānga e rite i taero pērā i "Ekzorran", "Radotera", "Aspen", "Krotenal", "Tetlong", "Refuzal", "Stoptil", "Antietil", "Kontrapot", "Tetradin", "Antietan" "Dizetil", "Alkofobin", "Aversan", "Anticoli", "Antabuse", "Esperal", "Lidevin", "Abstinil".

Kia pehea te nui Ko te tarukino "Disulfiram"? Ko te utu o tenei tarukino i roto i nga papa awhe 200-1000 moni (i runga i te kaiwhakanao rānei). Ki te whakaaro ki te āhua ētehi, me te otinga hinuhinu, e taea te hokona ratou mo 600-2400 moni.

He pai te nuinga arotake o te waihanga reira. Ko reira taa'eraa e te maha whakamahia tenei tarukino mō te maimoatanga ngaro o te iwi ki te waipiro. e kore e tohunga tūtohu hoatu tenei whare, kahore te matauranga o te manawanui.

E ai ki te urupare o te hunga e whakamahia te tarukino whakaaro reira rawa tōtika whawhai te inanga, ki te tango i te horopeta hou o te waipiro. Tikanga, i muri i te fariiraa i te raau taero i roto i te manawanui whakatika whakakonekone ki waipiro. Ki te haere te inu waipiro i muri i te whakamahi i te raau taero, faatupu te reira i dyspepsia whakapeka, Makere, asthenia nui, tachycardia, a tae noa hypotension whakawehi.