Waikawa Zoledronic: pānga pharmacological me analogues

Kei te mohiotia te reira e bisphosphonates ahu ki tautāwhi i te whanaketanga o te wheua metastasis, me te ārai i wheua mate. Ko tētahi o nga taero pai no ki tenei rōpū - waikawa zoledronic. Ano, i reira he taunakitanga e tenei raau kua angioneogenesis inhibition, puku whakaekenga, adhesion o ngā pūtau puku i roto i te kiko wheua, te Kereru apoptosis, a reira he tahitanga ki te hahau.

Waihanga 1 oko

monohydrate waikawa Zoledronic - 4.26 Excipients mg - Konutai citrate, D-mannitol.

Pūtaiao

He inhibitor o wheua resorption. no te waikawa Zoledronic ki te piha haapiiraa hou o te piha haapiiraa teitei o bisphosphonates. He he pānga whiriwhiri i runga i te wheua. Te whakaiti i te mahi o osteoclasts, kahore meinga he pānga kino i runga i te hanganga me te tahi atu mau huru maitatai o te wheua kiko. hāngai ana te pānga o bisphosphonates runga wheua te i runga i te faitatau tiketike ki te wheua mineralized, engari te huarahi pū o ngā rāpoi ngota e whakarato hëoi te mahi o osteoclasts, ki tenei ra e kore kua tonu i ako. Hoki te mea he āhuatanga anti-puku tika, te whakarite tōtika i roto i te wheua metastasis.

I roto i te vitro kitea taua waikawa zoledronic, te Kereru apoptosis me te hëoi tini o ngā pūtau he tika te pānga antitumor runga myeloma, me te i runga i ngā pūtau mate pukupuku o te uma, i te whakaiti i te mōrea o te metastasis. Ano, waikawa zoledronic he taonga o te whakaiti i te kukū konupūmā i roto i hypercalcemia serum, meinga nei e te puku.

Tuhinga

• pāpaka Osteolytic i roto i aronga myeloma maha.
• Osteoblastic, osteolytic metastasis wheua whakauru o te pukupuku nui.
• Hypercalcemia, meinga nei e repara.

contraindications

• Pregnancy me uma-kai.
• iti hoki tākihi.
• Tamariki me ngā taiohi (kore kua haumarutanga tono i whakapumautia).
• Hypersensitivity ki bisphosphonates me te waikawa zoledronic.
• Whakatūpatotanga: pōrearea tākihi, huangō arahau, kore ate.

pānga taha

Anemia, thrombocytopenia, ānini, whanoke, pīkaru, whakapairuaki, anorexia, ruaki, korere, mamae wheua, arthralgia, hypophosphatemia, hypocalcemia, kirika, rewharewha syndrome, rohirohi, taonga taimaha. I roto i te maimoatanga o te tūroro ki te waikawa zoledronic te tahi mau taime kitea te whanaketanga o te osteonecrosis o te kauae (te tikanga i muri i te wawaotanga hāparapara, tiaki niho).

dosing

maturuturu rō-uaua, me i roto i te 15 meneti, engari kahore iti. Metastases o myeloma maha horopeta o 4 mg kotahi te marama tūtohutia. A, no te hypercalcemia, meinga nei e te puku mārere, he horopeta o 4 mg kotahi ia.

Ara

Kia whakahaere te tarukino, he mea e tika ana ki te whakahaere i te kukū o te konupora, ūkuikui, creatinine me te konupūmā i roto i serum toto. Ki te taea, e tūtohu ana ki te karo pokanga niho.

waikawa Zoledronic. analogs

Drugs "Actonel", "Aneldronat", "lyophilisate Areda", "Bonviva", "Bondronat", "Bonefos", "Klobir", "ksidifon", "Lindron", "Ostalon", "Ostealen", "Osterepar" "Pamidronate", "Pomegara", "Rizendros", "Strongos", "Tevanat", "Foroza" "Fosamax", "Fosfoteh", "Rizarteva".

waikawa Zoledronic. utu

Tikanga, pae whai wāhi i roto i te tohatoha o ngā rongoā i roto i te ture, tohu nga utu mo o ratou taonga. Ko, piro nui, kei te nuinga o tohua te utu o te waikawa zoledronic āhua. Engari fakafuofua'i 'ona uara tae e pā ana ki 14 mano moni ia pounamu. Hokona i roto i pharmacies i te whakahaunga anake.

tikanga te kōrero i runga ake ki te waia kaimahi hauora. Tenei tuhinga Ko e pā ana ki te kore e waikawa zoledronic whakakapi tohutohu tohu o te tākuta, a kore e taea te hoatu i te taurangi o te pānga pai i te whakamahi o te raau taero.