Tohutohu mō te whakamahi - ampicillin

Tino he i mua, ka mohiotia ai e te huarahi matua o te urutau o rerekē momo o huakita ki paturopi ko te β-lactamase me o ratou hua. Ko ratou tino whai hua i roto i whai wāhi ki te whakangaromanga o nga mowhiti paturopi tiaki, me te tata taka ranei to ratou pānga haumanu. Hei hinga tenei pānga kino, kua whakawhanakehia reira me pūhui matū rite ngā e Tautauā β-lactamase ko matua clavulanic waikawa formulations sulbactam me tazobactam.

Ēnei pūhui ngā rite huānga o te rongoā paturopi ingibitorozaschischonnyh pera-ka karanga - ngā taero, e ngā rongoā paturopi paturopi. tauira o taua teuteu mohiotia whānuitia he ampicillin-sulbactam, amoxicillin, ticarcillin me etahi atu e whakatu te rōpū o penicillins. Ratou whakamahinga he whai hua hoki no ratou e taea e mahi hei wāhanga o te whānui o ngā o momo te cephalosporin o III whakatupuranga, i te whai huatanga o te whakauru kaha noho i te taumata tiketike.

I roto i ngā ngā, kei te whakamahia i roto i te maha taero hou kei roto i te paturopi hanganga me inhibitors o β-lactamase, i reira te mea he penicillins houtanga mahi tuatahi, me te e tata rawa whakahokia ana e ratou o ratou miramira whakaora i roto i tohe nei i te nuinga o mohiotia hoki anaerobes tenei ra staphylococci me Gram huakita. I tua atu, i roto i taua formulations te whakawhānui ratou tūāwhiorangi antimicrobial. no taua tarukino ki te ampicillin / sulbactam, e tonu i runga i te kaiwhakanao kei taea te hua i raro i te ingoa unazin Sulatsillin ranei.

Tenei rongoā ngā ampicillin me sulbactam, e he hakari i roto i te ōwehenga o te 2: 1. Ka rite ki tohua e te ako ā-ringa, ampicillin me te sulbactam i roto i tenei faaineineraa anake mau ārai β-lactamases i te mahi tika korerotia ki Neisserial me atsinetobakterov.

Ko te tikanga mo te raau ā-ô whakaritea sultamicillin, tito o sulbactam me ampicillin. Papa to ratou fariiraa riro roto ki te tinana. Katahi te tauhohe o paparetanga me te pānga ngā ngā te ampicillin tarukino me te sulbactam, e whakatairanga ana i te bioavailability o ampicillin taumata ara teitei i uru e te ka te fariiraa i te horopeta rite o ampicillin tuku iho.

he whānui rawa hihinga o mahi, me tenei tarukino. Na reira, whakaaturia te whakamahi o te nuinga o taero i roto i mate o te TTP takenga kitakita, Sinusitis āhua rerekē, me te etiology. whakaritea te rongoā i roto i mate o te wahi o raro romahā: Bronchitis, kakā.

E ai ki ngā tohutohu mō te whakamahi, ampicillin he whai hua i roto i te maimoatanga o ngā ngā o mate intraabdominal me papatoiake, tae atu ki ngā mate ngohengohe kikokiko, wheua me mate tahi, te septicaemia ki te ihirangi sulbactam.

Ko te faaineineraa o te ampicillin ki sulbactam tino atu whai hua whakaritea ki te amoxicillin / clavulanate i te maimoatanga o te mate e kua tīmataria atsinetobakterom.

Ko te inenga o te raau taero whakatau nga tohutohu mō te whakamahi. whakaritea Ampicillin te-waha, te horopeta hoki ngā pakeke ko ahakoa o te kai i 0,375-0,75 karamu e rua nga wa i roto i te ra, ki te ko te mate ngāwari pūāhua. I roto i te puka atu nui o te rongoā e whakamahia ana e 1.5-3.0 karamu, puta noa i te ra, ka nui haere te pakeke te, e taea te nui haere te inenga ki te 6.0 karamu.

Ngā pēpi raau e whakahaeretia ana i roto i te pota tatau e pā ana ki 50 micrograms ia ra ia tetahi manokaramu o taimaha o te tamaiti. kawea Urunga te i roto i rua.

puka Tuku me inenga o te tarukino whakaahua ana i roto i te taipitopito te tohutohu mō te whakamahi. taea hoki Ampicillin tangohia nga papa i roto i te puka o te paura whakamahia ki te faaineine i te whakatārewatanga motuhake (ina waha whakahaere) anake. Na whakaratohia te whakamahi o te raau taero na roto i te werohia, mo tenei kua whakaputaina reira i roto i te puka paura. Te whakarewa tukua ki te tarukino i roto i te mōkihi kotahi.