"Nimesulide" pire. Tohutohu mō te whakamahi, ritenga tūturu

Pain - Ko te ahua o te ngana o te tinana ki te kukume i te aro o te tangata, karanga hoki te tauturu. Na he e te tahi mea "i roto i te basileia Danish", me nga rauemi o te tinana e kore he nui ki te whakatika i te raruraru, e hiahia ana matou tautoko i te waho.

Kiritaki mākete ho'oraa o te Russian Federation aroaro rau o taero ki te āwhina iwi faaruru i te mamae. rongoā katoa rerekē hanganga, whānuitanga me te tikanga o te mana. Ko tētahi o te whai hua tino ko nga raau taero i te rōpū o kore-steroidal taero anti-inflammatory. I roto ia ratou Ko te whakatārewatanga me papa "Nimesulide".

Hanganga me te Composition

papa a tawhio whai te āhua lenticular. I roto i te te tae kia koma kōwhai ranei kōwhai noa. Ko te wāhanga matua hohe - he taonga Nimesulide i roto i ia papa - 100 mg. Mai taea te huaina he maha atu cellulose microcrystalline, māngaro (kānga), te konutai māngaro glycolate, colloidal hāorarua silicon.

I tua atu, kua whakaekea te tarukino ki kiritaki i roto i te puka o puehu mō te whakatārewatanga "Nimesulide." Ko te rite i o papa, ia 100 paihere mg wähanga kaha matua hanganga.

pharmacodynamics

Nimesulide tīpakongia inhibits cyclooxygenase-2, cyclooxygenase-1, tona pānga kei ki te whānuitanga nui iti. I roto i tenei whakaaro, te inhibition o prostaglandins kōtuitanga kitea whakapataritari tauhohenga inflammatory. Heoi, ko te hanganga o te prostaglandin-momo nimesulide ture puai pānga papaki rangona, hua i roto i faaiteraa whakakapi iti o te pūnaha kūnatu.

I tua atu, i te mahi whai hua o te nimesulide whakakitea i inhibition o te hanganga o Radicals free. Heoi, e kore e nga tukanga o te hemostasis me phagocytosis mamae nga pānga o tenei taonga. Ko te tikanga o te medicament pānga anti-inflammatory fakahaa'i noho nui wāhi me tona kaha ki te pehi i te tuku o te myeloperoxidase (i roto i te maha mate inflammatory taea meinga kino kikokiko, ko reira tetahi o nga āhuatanga tātaritanga tika tino tohu o te tūpono o te whakaeke ngakau patunga ranei).

Tuhinga mō te whakamahi

Whānui nui whānuitanga o te tarukino "Nimesulide". I te mea hanga tenei tarukino? No te mea kua te tarukino i runga i te pānga matatini tangata - antioxidant, analgesic, antipyretic me anti - ka te whakaritea ai ki te maha o mate inflammatory. tarukino tōtika me te i roto i te aroaro o te osteoarthritis (mate tahi ma'i i roto i te wahi tuatahi ngaro te ngohe articular), tendinitis (mumura o iohere me kiko e hōloa), bursitis (mumura o nga peke mucous, kaha i roto i te hononga).

hua pai tohu "nimesulide" i roto i te maimoatanga o te kaikōiwi, anō-articular mate rūmātiki. I momoho te whawhai ki mate hopuhopu e kua haere tahi e te tukanga inflammatory. Tino maha, "Nimesulide" papa whakamahia i roto i te gynecology, te maimoatanga o te whara o te take mai rerekē. mea tūroro te whakakorenga whai hua o te mamae i roto i whakanohonoho postoperative.

Contraindications "nimesulide"

Mai pā ana te medicament ki te rōpū o te hou National Hui Square, kua reira tino he rārangi whānui o contraindications. "Nimesulide" (i te mea tauturu te rongoā - kua kōrero i mua) e kore e tangohia e te iwi ki te hypersensitivity ki tetahi wae i roto i tona hanganga. puta No raau whakahaere ki te hunga tūroro ki te hītori tauhohe hepatotoxic me hohenga hypersensitivity rite Rhinitis, bronchospasm, urticaria (ki ahipirini atu māngai NSAIDs o te rōpū ranei).

Contraindications ki te whakamahi o te medicament ko ki te whai i tetahi pāpaka erosive-whai puku o te pūnaha kūnatu, te hehema ki te whakawhanake i toto o tetahi take (t. E. momo i roto i te mahi o te mafiti toto).

Medicine "Nimesulide" ako opani tūroro ki täkihi, ate, iti hoki cardiac. Tūroro ki "ahipirini" huangō, waipiro me te ti'aturiraa tarukino, me te kore e tango i te tarukino.

Kaua e whakahau rongoā i roto i aua wā, ki te nui haere te manawanui kei te e kitea pāmahana tinana atu tohu rewharewha-rite ranei. I tua atu, he te tautokohia ki te tango "Nimesulide" tamariki, hapu me te wahine lactating.

tauhohe taha pea "nimesulide"

Taupānga o te medicament taea meinga he maha o ngā pānga taha i te ngā whēkau me ngā pūnaha o te tinana tangata.

Kua tuhia te tauhohe tino noa i te pūnaha kūnatu, a kua whakakitea e ratou i te whakapairuaki, ruaki, korere, flatulence, me te whanaketanga o te gastritis. Iti maha puta toto gastrointestinal, mariao noa perforation. Taime e taea e koe te whakarongo e pā ana ki dyspepsia, stomatitis, mamae puku.

Ka taea e meinga "nimesulide" taha mahi e te pūnaha hepatobiliary, tino maha whakakitea i roto i nui haere ngā taumata ate whākōkī, i te iti rawa - i roto i te whanaketanga o te kakā (tae atu fulminant ..), Cholestatic jaundice.

I runga i te tauhohe o te pūnaha Cardiovascular taea mea, ki te mea i reira te mea he ara on i roto i te pēhanga toto, tūroro uaua māharahara e pā ana palpitations ngakau, toto, Makere, hūpeke te pēhanga toto.

pūnaha mimi taea te whakautu ki te ahua o te edema (e kore e maha), uaua - pupuri mimi, hematuria, dysuria. Tino uaua kia whakawhanake reira täkihi, pauku interstitial, oliguria.

tauhohe pea o te CNS te tino maha whakakitea e whanoke, ahuatanga, asthenia. Iti maha taea te rongo e pā ana ki pāhoahoa, te whanaketanga somnolence (faitatau hypnotic moe), syndrome o Reye (encephalopathy), hauhauaitu (tinana pāmahana heke i raro i te taumata e hiahiatia ana ki te mau tonu pākia noa). Taime e taea e koe te whakarongo e pā ana ki taua tauhohe "Nimesulide", rite pau te, manukanuka, ri'ari'ai.

Ki te whakaaro ki te pūnaha lymphatic me te pūnaha hematopoietic, "Nimesulide" (ture, paramedics arotake whakau tenei mōhiohio) kia uaua whakapataritari anemia, eosinophilia, ano iti pea ki te whakawhanake i thrombocytopenia te purapura pantsitopenicheskaya.

Varavara, engari ka taea e koe te whakarongo e pā ana ki te raruraru pūkoro (hyperkalemia), pūnaha ārai mate (hypersensitivity, anaphylaxis), nga whekau o whakakitenga (kite te peroo, puputu'u 'o te mara), romahā, mediastinum (patua dyspnea, bronchospasm, huangō). He nga tauhohe o te kiri, me te kiko subcutaneous (sweating, minamina, dermatitis, urticaria, erythema, rawa uaua - paitini epidermal necrolysis, Stevens-Johnson syndrome).

aratau dosing me te ara iahiko tono

papa tūroro Pakeke "nimesulide" tohutohu ki te tango i tetahi i te wa (100 mg) rua rā. Ko reira pai ki te rave i te reira i muri i te kai, me te inu nui o te wai mo te rongoa. Ki te mea he puehu mo whakatārewatanga, ka diluted nga tirotiro o tetahi paihere i roto i te 100 ml o te wai. Taiohi i runga i 12 tau o te tau i reira he kore hiahia ki te huri i te horopeta, me nga kuao i tenei tarukino ki whiwhi rāhuitia. I roto i te take o te maimoatanga o te tūroro ruhiruhia e kore e whakamana i te whakatikatikanga horopeta.

Hoki te iwi e mate ana i te iti hoki ate, creatine whakawātea i roto i te whānuitanga o te 30-80 ml / min., E kore te mea tika te inenga. Ki te tuku iho te tohu kei te (30 ml / min iti ranei.) - riria mai ki te farii i medicament.

Ko nga tūtohutanga matua mo te fariiraa o te tarukino "Nimesulide" enei. whiriwhiri te inenga te minimally whai hua, a mo te wā ka taea poto, e ka whakaiti i te mōrea o ngā pānga kōaro. e kore e nui te akoranga mōrahi o therapy ki te whakamahi o "Nimesulide" 15 ra.

inenga nui: tohu, Treatment

Ka mau i te pire "Nimesulide", he mea e tika ana ki te piri ki te pota tūtohutia i roto i te tohutohu tīpakohia ranei i te rata haere. Whaiaro-whakahaere o te medicament me (ranei) tona whakamahinga whakakeke taea hua i roto i te tuwhena rawa. Ko te tino pinepine kitea nga tohu e whai ake nei: whakapairuaki, ruaki, toto, wahi gastrointestinal, te momoe, lethargy, takawhita (pēhanga toto tiketike), inhibition o te mahi romahā, whakapeka täkihi.

Maimoatanga i roto i te take o te tuwhena rawa symptomatic, kei te tautoko huru. Kei te ngaro nimesulide raau tēnei wā. Ki te mai i overdosing tango i te horopeta nui o medicament ranei e kore e haere neke atu i te 4 hāora, te manawanui ko te hōhipera lavage pekitīlia fariiraa tūtohutia absorbent (hei tauira, whakahohe waro i roto i te nui o 60-100 mg mo te pakeke) me etahi momo o te tarukino wāhine osmotic.

I roto i te wā katoa o te maimoatanga kia āta aroturuki e ngaio hauora mahi ate me te tākihi. e kore te mea e wātea ana ngā mōhiohio e pā ana ki te taea o te tango o nimesulide i te tinana i te tātari toto. No te mea o te tohu tiketike o te tarukino here ki pūmua kore he whai hua diuresis takoha.

tohutohu motuhake

"Nimesulide" ki te whiwhi i te whakahaunga i pharmacies kahore e i hiahiatia, Heoi, kia tangohia ki te tūpato. A ape i tono whakarara o te medicament me tetahi atu kore-steroidal māngai anti-inflammatory, Pë kaitiaki. Ki te whanaketanga o nga tohu o tūroro, ate kino āhuatanga (whakapairuaki, ruaki, anorexia, mimi pouri) ranei whakanui ake i te taumata o te transaminases ate tono "nimesulide" kia mahue. Ki te reira te mea he kirika tohu rewharewha-rite ranei, kia mutu tonu therapy.

Tahuri ki tona tūroro kia e i roto i whakarara ki te "Nimesulide" rongoā tango e whakanui i te mōrearea o keha gastrointestinal me te toto. Whakatūpatotanga i whakaritea tarukino mō te iwi e mamae i te colitis ulcerative ranei te mate o Crohn, tuwhenua he hītori o tūroro ruhiruhia.

Tangata e Me ki te tango i "Nimesulide" me ki ahipirini i roto i pota cardiac me whakaritea huinga therapy ki gastroprotectives.

Ko te whakamahi o "Nimesulide" (ranei tetahi atu NSAID) i roto i ngā rahinga nui, me te mo o te wā he wā roa arata'i ki te hua iti i roto i te mōrea o aituā thromboembolic (patu, infarction myocardial, a na i runga i. N.).

kia whakaritea ai tūroro ki ngā raruraru pūnaha "Nimesulide" Cardiovascular anake, ki te nui te painga e tūmanakohia te mōrea o ngā pānga taha.

Ko te medicament he pānga i runga i te tohu o te mahi mōtepe. He nui hoki ngā tūroro mate ana i hemorrhagic diathesis tenei mōhiohio. pāpaka nui o te kiri tino maha whakawhanake i roto i te whakamahi wā roa-"nimesulide". Kia puta rashes kiri, riro kino appreciable ki kiriuhi mucous tetahi atu faaiteraa whakaritea o te ātete kai ranei, kia mutu rongoā therapy.

Ko te whakamahi o "Nimesulide" wahine hapu taea tīmata kati tau mahani matua i mua i te hiahiatia reira, whakaiti i te rōrahi o te waikahu. Pea nui ake te mōrea o te toto intrauterine, he vaivai o mahi, te ahua o te edema. Hoki enei take, whaea expectant i roto i te tuatahi, me trimesters tuarua o te hapūtanga fariiraa "Nimesulide" te kore tūtohu.

Me waiho te reira i te whakahoki ki te pātai o mehemea e taea te tango tatou i te "Nimesulide" wā kotahi me te waipiro, he kitea reira: e kore te he huinga taua tukua!

analogs

I raro i analogs "nimesulide" e pā ana ki taero i ngā rōpū NSAID kei roto rite te matua nimesulide whakauru hohe (utu mo e oscillate ratou i āhua i te whānuitanga taua, engari paku raro reira). Ko te analogs kaimahi hauora tino mohiotia, me te nuitia whakaritea ngā taero "Naiz" (rā, papa, whakatārewatanga), "Nimesil" (puehu) "Niemiec" (papa) 'nimulid "(rā, papa, papa whakatārewatanga hoki ngote) .

riro analogs katoa rawaka pai, ka whakaritea ki te mahi ki te whānui o mate, inflammatory huru mau ngā.

awhe utu

He āhua Prices hoki ia "Nimesulide" me ona analogs te taua, ahakoa whakaaro matou ake wātea utu tarukino ki te whānui o kaihoko ngā. Papa "Nimesulide" (20 RW. I roto i te mōkihi) ka utu 85-90 moni ia mōkihi. Ko te taua maha o papa "Naiza" ka utu 110-140 moni, "Niemiec" (ano 20 RW.) - i roto i te moni 115-134. Packaging "nimulid" o 30 pire utu 180-220 moni. Ko te ihirangi rōrahi o te whakauru matua kaha (Nimesulide) i roto i analogs katoa taua - 100 mg.

Engari papa "Nimesulide" (utu i raro) e taea te whiwhi, hei tauira, he slurry "Naiz" utu 200-300 moni 60 ml ranei "nimulid" - 75-105 moni mo te nui ano o te tarukino. e wātea ana hoki te whānui o kiritaki ngā ano rare "nimulid": 20 hea i te utu 130-155 moni ia mōkihi.

Mahalo te puka tino utu o tuku o te tarukino me te nimesulide rite te wähanga matua - he paura 'Nimesil ". 30 peke (mōkihi) ka utu te kiritaki i roto i te nui o i 560 ki te 645 moni.

Hoki tono wā he hāpiapia whai hua ki te nimesulide. Ko te kupu, "Naiz" ka utu 120-145 moni mo te ngongo o te 20 g 215-275 moni (50 g) ranei. Rā "nimulid" he iti bit iti: 115-150 moni ia rōrahi ngongo o '30

Roto i te whakamutunga e hiahia ana ahau ki te mea i te whai. Ko te whakatau ki te whakamahi i "nimesulide", tetahi orotahi tetahi atu NSAIDs ranei kia tangohia e te rata haere. Anake e taea tika te ngaio hauora te aromatawai i te pakeke o te hauora o ratou tūroro, ki te whakaaro mate e pā ana katoa, whiriwhiri te inenga tarukino ki te tīpako me te whakawhanake i tētahi mahere maimoatanga i roto i te tikanga ki te whakaiti i te tūponotanga o ngā pānga taha me ki te tiki i nga hua tino pai.