Histidine: tātai, tauhohe matū

whakaaro takitaha o tatou i te iti rawa kotahi i roto i te ora e pā ana ki tona kai. Here, mo te tauira, he aha te täkupu rā o ngā matū e hiahiatia ana e te tinana mai ki a tatou ki te kai? He aha e waikawa amino hiahia tatou, a mo te aha? I teie mahana, tatou, o te akoranga, kia kore a te kōrero e pā kai tōtika tika rite te katoa, mai i tenei tetahi iti me tuhinga noa te tatini. korero matou kotahi anake taonga, i te mea kore rawa nui mo te tinana. amino tēnei histidine waikawa. oro Ko tōna ingoa matū uaua - L-2-amino-3- (1H-imidazol-4-yl) waikawa pōwaro. Ko nga mea tuatahi te tuatahi.

He aha e waikawa amino?

I mua i aparau i tatou nga āhuatanga o te histidine me tona tūranga i roto i te tinana, ka matau tatou ki te wā "waikawa amino". Te hunga e aroha o hākinakina, kua rongo e pā ana ki enei matū. He waikawa amino ko he pūhui organic he rua taketake rōpū mahi e hanga motuhake ai: ko te rōpū amino -NH _2, me -COOH rōpū carboxyl pera-ka karanga.

Ko te tuatahi he kawenga mō te āhuatanga taketake o tenei piha rerekē o pūhui. Nā ki te hauota, me ona irahiko takirua waikawa amino taea te hanga pai i ako katote. A, no te tahuri te rōpū amino te konei i roto i taua ngota: -NH ₃ ^+.

te rua te rōpū mahi kawenga mō te āhuatanga waikawa. Ko reira, e nehenehe o foaki he iraoho, hoko anion -COO ^-. he āhuatanga taua āhei hanga tai ki te rōpū taha carboxyl.

Ko te kupu, e rua nga wahi, ia o nei te mea nehenehe o te hanga tai te waikawa amino. Ko tētahi o ratou whakarato nga āhuatanga o enei pūhui, waikawa, me te tahi atu - te whenua. I roto i te whānui, e taea te māngai te waikawa amino rite: NH ₂ -CH (R) -COOH. Reta R ki kia matau ki konei rite "tuwhena", i.e. tetahi matūriki organic arā, o te rōpū mahi me te kōhiwi waro me ahei o te hanga i te here (here ranei) ki te waikawa amino tïpako rāpoi ngota.

Ka rite ki te tikanga, ara te hunga e kore e mōhio ki te Pūtaiao me te kore hiahia i roto i te hākinakina e, kotahi rongo, i te iti rawa i te pānuitanga, e te waikawa amino hiahia tatou, a ka he rawa āwhina. Kia kite a he aha te mahi mahi ratou i roto i te tinana, me te aha e hiahia ana koe ki te tiki i a ratou i roto i te auau e hiahiatia ana o te kai.

Amino mahi waikawa i roto i te tinana

Ka rite ki matau koutou, kua hanga ake katoa o tatou o te pūmua, te ngako, me te warowaihā. A, kia rite ki pau tatou ratou rite kai ki te mau tonu tona noho tuwhera tonu. Ko te kaupapa o tēnei tuhinga, e paanga tatou pūmua anake. Ko te rāpoi ngota nui tenei, e mahi ana i te mahi tino rerekē, me te tino nui i roto i to tatou tinana: waka o matū, te hanga o ngā pūtau hou, e whakakaha ana i te hononga i waenganui i neurons roro. e korero tatou e pā ana ki te kore noa pūmua. Ko te meka e hanga enei matū katoa ki runga o waikawa amino, e ai ngā histidine. Tātai ara te pūmua māmā ngā i te iti rawa tekau waikawa amino, hono i roto i te mekameka polypeptide. Ia o ratou kua ona ake hanganga, me te āhua e taea ai ki reira mahi i te mahi mo te i hanga ai e te natura.

histidine

Ko te tātai ngā tetahi waikawa amino, i kite ai matou, rōpū i te iti rawa e rua mahi, me te koiwi waro, tūhono ratou. Ko Ko te aha te rerekētanga i waenganui i nga waikawa amino katoa (e, rokohanga, kua kitea e kua he torutoru miriona) ko te roa o te piriti waro i waenganui i te rōpū e rua i roto i te hanganga tuwhena, adjoint ki reira.

Ko te kaupapa o tēnei tuhinga - ko tetahi o te waikawa amino - histidine. Tātai uaua tenei waikawa mahuinga ia. Ko te mekameka waro matua i waenganui i te rōpū mahi e rua kite tatou i tetahi anake ngota waro. I roto i te meka, proteinogenic katoa faufaa (taea o te hanga pūmua) waikawa amino hoki anake kotahi ngota waro i roto i te mekameka. I tua atu, histidine kua he huringa ngā tuwhena hanganga uaua. I runga e taea kite koe i e ko te histidine. Ko te tātai, ko te hanganga āhuatanga o e ngā i roto i te heterocycle (whakaurunga o tetahi atu ngota anake waro), ko mau e kore te taonga faingataa.

Na, kotahi kōrero matou nga ariā taketake, kia neke a ki te tauhohe e taea te kawea ratou ki te histidine.

āhuatanga matū

Tauhohenga, e tango tenei waikawa amino, he tino onge. Atu tauhohe ki te waikawa me turanga, tomo te reira ki te tauhohenga biuret ki te hanga i ngā hua tae. I tua atu, histidine, tona tātai ngā kia tali toenga o imidazole ki te waikawa sulphanilic i Pauli tauhohenga.

mutunga

Pea katoa o nga tūemi nui Taka matou. Te ti'aturi nei tatou e ko whai hua ki a koutou i te tuhinga, ka hoatu e koe te matauranga hou.