"Celecoxib": tohutohu mō te whakamahi, arotake. analogues tarukino

Maimoatanga o mate e pā ana ki te kino ki te pūnaha musculoskeletal, tono i te mākete ho'oraa waihanga taero hou ki iti pānga taha me te kakama nui. Kua kitea Scientists, a synthesized he whakatupuranga hou o kore-steroidal taero anti-inflammatory i runga i te pūtake o te celecoxib. Kua heke ēnei taero tāoke me te pai noatia e te tinana.

Whakaahuatanga o "Celecoxib" tarukino

Te matū celecoxib he tae kōwhai ha ma, me te pā ki te coxibs rōpū e whakaatu inhibition whiriwhiri o te momo tuarua cyclooxygenase. Medicaments i runga i nga pūhui o te hakari riro korerotia āhuatanga anti-inflammatory me analgesic. whakaaro te raau taketake i runga i te pūtake o te celecoxib te ki kia whakawhanakehia e te kamupene American "Pfizer" tarukino "Celebrex". ko reira ako a whakawakia nga āhuatanga pharmacodynamic o te tāoke ki te tinana tangata.

Ko te tahi atu medicaments kei roto i te taonga celecoxib kaha e kano, tae atu tarukino "celecoxib".

puka inenga

tarukino wātea i roto i te capsules gelatin pakeke i te inenga o te whakauru kaha, 100 mg me 200 mg. Rerekē atu kore-pūtaiaki māngai anti-inflammatory, e kore puka inenga hei hinu, rā, rongoā injectable te aukati ranei. Ki te tahi mau tūroro pōhēhē i huaina puka tuku "Celecoxib" tarukino - papa, ahakoa e korero tatou e pā ana ki te capsules.

hanganga

Ko te whakauru kaha he celecoxib taonga i roto i te nui o 100 mg me 200 mg. Ko te hanganga o capsules ngā wāhanga pŭpŭ tauturu e whakarato whakakī wāhi, te flowability me te pūmautanga o te ranunga granulated. Ko ētahi o ēnei reihuka, te konutai lauryl pūkawa, polyvinylpyrrolidone (K30), te konutai croscarmellose, konupora stearate.

Āpitihia ki te ā-tarukino "celecoxib" ako Kei roto te hanganga me te ahua āhuatanga o te anga gelatin capsule. E ai ki te whakaahuatanga, puhoi titiro reira, i tata ma i roto i te tae, me te tohua ki te tohu "100" ranei "200", kei runga i te ropu puru kōwhai ranei, aua. Tenei taea ki te wehewehe capsules ki toketaá rerekē. Kei te pania ano Composition o Inks kōwhai me te puru taipitopito tohu waikano mahaki ki kaiao.

raau taero rite

Rongoā hua "Celecoxib", analogues o e kei hoki te taonga celecoxib kaha, ka taea e whakaatu te pānga haumanu taua i runga i osteoarthritis o te kōhiwi tangata.

Ko te tarukino taketake "Celebrex" me ona kano "Celecoxib", "Artoksib", "Zitsel", "Revmoksib", "Ranseleks" e whakaaro rongoa whakawhiti. Heoi, ka utu i te kāwai utu taketake te tikanga o te nui atu te utu atu i to ratou ritenga.

I roto i te faaineineraa "Celebrex" Kei celecoxib i te inenga o te 100 me te 200 mg rite te medicament "celecoxib". kia rerekē wāhanga Houalotú o te capsule me tona pūhera e rua i roto i te hanganga kounga, me te ine e kore e e pā ratou āhuatanga. No nia i te ahua o te tuku o kano "Celecoxib" analogues tarukino e hua anake i roto i capsules gelatin pakeke mō te whakamahi ā-.

He kore-steroidal anti-inflammatory āpiha, cyclooxygenase rite hāngai ki te rua o te momo, engari rerekētanga he i roto i te hanganga o te wae kaha, te pharmacokinetic me ngā āhuatanga pharmacodynamic. Ko ētahi o ēnei ko te pūhui nimesulide sulfonamide i roto i te inenga rā o 200 mg tōtika akono nga tohu o te osteoarthritis me kaikōiwi. Formulations i runga i tona pānga anti-inflammatory me analgesic i hëoi te cyclooxygenase tuarua me ki te whānuitanga iti - o te momo tuatahi, pā he momo o kaiwhakaako o te mamae me te mumura.

Ka rite ki nimesulide, celecoxib he māngai o te piha haapiiraa sulfonamide o matū, a hoki i roto i te inenga rā o 200 mg faaore tohu o osteoarthritis. e kore e tautāwhi i te reira i te momo tuatahi cyclooxygenase me mahi i runga i te maha iti o kaiwhakaako o te mamae me te mumura.

He coxibs maimoatanga kē whakahaere waha he momo injectable o NSAIDs. Ko tētahi o nga painga matua o "Celecoxib" hua - te utu. Werohanga (ampoules hoki werohia) utu atu te utu atu kore-steroidal taero anti-inflammatory, engari he tawhiti pai ki te hua i te whakamahi o te raau taero i roto i te puka totoka taua pai i werohia.

tikanga o te mahi

Drug "Celecoxib" - he tarukino e tohu ana he whakatupuranga hou o nonsteroidal māngai anti-inflammatory, anti-inflammatory, analgesic, mahi antipyretic. e pā ana tōna tikanga o te mahi e ki te ārai i te hanganga o prostaglandins inflammatory mā te whakaiti i te mahi o Cox-2.

tauhohe inflammatory tīmata te whakaurutanga mai o te momo tuarua cyclooxygenase, i tahuri accelerates te haaputuputuraa o te prostaglandin kōtuitanga me matū e whakarei mumura. State whakawhanake ngawhatanga me te mamae.

e kore e Cyclooxygenase momo tuatahi pā te haumanu horopeta "celecoxib" faaineineraa. Tohutohu mō te whakamahi whakaahua ana te tūpuku o te tarukino me te faatura ki tenei paru e pā ana ki ona mahi o ngā tukanga whaiaroaro tupu i roto i nga pūtau o te api parau, me mōtepe hanganga gastrointestinal.

Ano, i roto i nga tohutohu i homai raraunga i runga i te pānga o te raau taero i runga i nga whatukuhu. I raro i te mahi o te celecoxib he iti iho i te whakaaturia i roto i te mimi hanganga prostaglandin E2 ko F1 o 6-keto-prostaglandin, engari e kore e huri i te tohanga o te B2 11-dehydro-thromboxane, e tohu te rongoā pānga whiriwhiri.

e kore e Whakamahi o te tarukino "Celecoxib" arahi ki te hekenga i roto i te auau filtration i roto i te glomeruli tākihi ruhiruhia me i roto i te tūroro ki te iti hoki tākihi.

Tuhinga mō te whakamahi

E ai āhuatanga pharmacodynamic o te faaineineraa "celecoxib" tono ka waiho reira whai hua mo te maimoatanga o te kaikōiwi me psoriatic, mumura ma'i ki te mamae o te tuaiwi me sacroiliac hononga, me te osteoarthritis.

Nā ki ona āhuatanga analgesic whakamahia mō te huru fakamamahi i roto i te mamae musculoskeletal i muri i te maimoatanga hāparapara, dysmenorrhea, haere tahi nei i paheke mamae. hāngai ana te pānga anti-inflammatory o te tarukino te i whakaiti outgrowths me polyps i roto i te kopirua me tōu i roto i te tātaritanga o "polyposis adenomatous".

Me pēhea te ki te tango i

Tangohia rongoā "Celecoxib" tohutohu mō te whakamahi e kore taunaki roto tūhono ki te kai o te kai. E kore e nga capsules whakatuwhera me kahore te kokokiko,, ka horomia katoa i nui o te wai inu.

Ko te nui mōrahi o celecoxib, e ai kia tangohia ia ra ko te 0.4 g whakamahia ana tēnei faaineineraa i roto i te taikaha anake i roto i wā onge.

Ka taea e pōauautanga Cardiovascular meinga pota tiketike, me te maimoatanga roa ki te tarukino "Celecoxib". Kei Guide mōhiohio i runga i toketaá iti mo te maimoatanga symptomatic o ia pānui. Whakarato tūtohutanga i runga i te whakamahi poto.

Hei whakakore i te tohu e pā ana ki osteoarthritis, me ankylosing spondylitis, ra tango tetahi e rua ranei nga wa ki te 200 mg o te tarukino.

Hei whakakore i te tohumate o te kaikōiwi te whakamahi i te horopeta rā o 200 400 ranei mg, i tangohia rite rua.

tukinotia dysmenorrhea tuatahi mamae, me te kei i te ra tuatahi te horopeta tiketike o 400 mg, me te fariiraa taea o te atu 200 mg, ia ra te whakamahi i 200 mg 2 nga wa i te ra.

Te paari, me tūroro he tohu ngawari iti ate ngawari ki te whakaōrite iti hoki tākihi ranei, kawea kahore te tātai ano o te horopeta i roto.

taimaha iti (iti iho i te 50 kg), te pakeke toharite o te kore ate - kāwai raraunga mō ngā tūroro tukinotia ki pota iti o te rongoā tikanga.

Tikanga, mo te maimoatanga o ngā tukanga inflammatory i roto i hononga e whakamahia ana ngā pūnaha maimoatanga e hāngai ana i runga i te whakamahi o te maha raau taero i roto i te mau huru ngā inenga. Whakakotahitia "celecoxib" capsule, hinu, rā-momo warming ranei "Apizatrona" ranei "finalgon. whakamahi Topical ai te pānga rangitahi, na kei te ratou whakamahia tahi ki taero mō te fariiraa roto.

opani te whakamahi o tenei

Ehara i tūroro katoa ki mate o te hononga, ka taea e te tango e koe i te tarukino "Celecoxib". Tohutohu mō te whakamahi Kei te rārangi o mate me ngā āhuatanga i roto i nei ake ka kino te taputapu i te pai. Ko ētahi o ēnei:

• pununga honé, huangō, huru mate pāwera i te mahi o te ahipirini me ētahi atu taero anti-inflammatory nonsteroidal;
• mahi whakaora e pā ana ki te AVC karo täpiritanga ;
• exacerbation o whewhe keté;
• puku, me te toto intestinal;
• mumura o te mucosa i roto i nga whekau;
• rahunga ngakau;
• mate rere pūroto o te uaua ngakau;
• mate o pera piringa me oko kaka ki te rere toto kaka waimaero;
• āhua nedostatochnosttyazheloy ate;
• nui täkihi;
• haputanga;
• whāngai ū i te pēpi;
• i raro i te tau o waru nga tau;
• hypersensitivity ki excipients;
• nui haere susceptibility ki te wae sulfonamide.

Ki te whakamahi tupato o te tarukino "Celecoxib" kia hei iwi ki mate o te wahi gastrointestinal e pā ana ki toto keté whewhe i roto i te mua, mate o nga huakita mucous o te puninga Helicobacter pylori.

pupuri i roto i te tinana, me te kopa ngohengohe edema wai, disorders o te ate tuarua atamira, ngakau me te iaia mate, i roto i te tinana, ai te hua i roto i te taumata cholesterol i roto i te wē toto kite lipid pākia, mate huka, te huka, mate somatic i kino, me te ko te take mo te mōrahi whakamahi tupato o te tarukino "celecoxib" i raro i te mātakitaki o te rata.

pānga taha

Ahakoa te whakatutukitanga auaha i roto i te hanga o te whakatupuranga hou o coxibs, e kore e kowaiwai o ngā pānga taha enei matū me taero e hāngai ana ki runga ki a ratou.

Tahi i te tarukino "Celecoxib" tohutohu mō te whakamahi, mua manawanui me tohunga - i roto i enei puna mōhiohio e pā ana ki te pānga kino taea e kia puta i roto i te whekau faufaa.

Te pānga kino taea i runga i te pūnaha kūnatu āhuatanga e NSAID-gastropathy, mamae i roto i te puku, whakapairuaki, ruaki, tokopā, whakaiti i te hiahia mō te horomanga kai me te korere. whakamahi wā-roa o pota tiketike taea meinga ulceration me te toto i roto i te membrane mucous o te puku, me te paru, toto pae, whakahohenga nui o te ate transferase.

E whakakitea disorders Nervous oaoa, ānini, whanoke, somnolence, ohoroa, āhua fakalotofo'í.

Tākiekina i runga i te pūnaha Cardiovascular tika ki nui haere te pēhanga i roto i te pera, me te tachycardia.

Te faaineineraa "celecoxib" whakaiti ātete ki ngā mate hopuhopu o te pūnaha romahā, e taea te whakahuatia i roto i te whanaketanga o te pakohu kakā, Rhinitis, pharyngitis, mamae i roto i te ihu me te korokoro, mare, dyspnea, bronchospasm.

Ko te pānga o te raau taero i runga i te rongo ai i te whakaiti i roto i te perception māna, me te ahua o te tinnitus.

I runga i te pūnaha mimi pā tarukino "Celecoxib" kia kia riro ai koutou täkihi ki te whanaketanga o te edema syndrome.

Ki te whakaaro ki te okana toto-hanga, ka taea e te raau meinga te faaiteraa o te agranulocytosis, anemia, leucopenia, thrombocytopenia.

kia puta rashes kiri ki te ahua o te pruritus mate pāwera, urticaria, photosensitivity, angioedema i roto i te kanohi rohe, pito, taihemahema.

āhuatanga fariiraa

Drug "Celecoxib" rerekētanga tūturu e pā ana ki te kaha ake te tūpono o ngā pānga kōaro i runga i te pūnaha Cardiovascular ārahi ki Thrombosis, infarction o myocardial auheke te uaua, me te patu. Tautautefito nga piki mōrearea i roto i whakahaere ma'i o te rongoā e tūroro i roto i nei i reira e mate Cardiovascular.

Ki te whakaiti i te tūponotanga o taua pōauautanga i roto i ngā tūroro tango i te tarukino "Celecoxib" whakahau te horopeta raro i te nuinga wā poto o te maimoatanga. kia aparau i te manawanui ki tō tākuta te tohu ka taea o te mate, me te ki te farii i tohutohu i runga i te āhua o ki te whakautu ina puta ratou.

te whakamahi i te huinga o te waikawa ahipirini i roto i pota iti ki te tarukino "celecoxib" Ki te whakaiti i te tohu Cardiovascular. Reviews o rata tohu te pānga antiplatelet o ahipirini ki kikokore te toto , ka tango coxibs, e kore e nei i taua āhuatanga anti-thrombotic. Tikanga, whakaaturia te huinga taua i roto i tūroro paari ki disorders o te pūnaha musculoskeletal me pūnaha Cardiovascular, nui haere te tāoke gastrointestinal te ka kore-whiriwhiri kore-steroidal taero anti-inflammatory. Otiia e kore e te te whakamahi o te celecoxib taonga ki ētahi atu NSAIDs tūtohutia.

Hoki tūroro mate i te pēhanga toto tiketike, te aroturuki tonu o tenei tawhā ka fariiraa i "Celecoxib" tarukino.

kia hoatu ngā aro ki te aroturuki i te huru o te kaiao i roto i ngā ki anticoagulant (warfarin) me matū antiplatelet (waikawa ahipirini, clopidogrel) te whakamahi i inhibitors whiriwhiri (citalopram, sertraline), hëoi inhibitors serotonin reuptake o CYP2C9 isozyme, puka papa glucocorticosteroids.

Ko te tarukino "celecoxib" whakatairanga i te hanga o prostaglandin matū, e faataere te wai i roto i te tinana, me te whakatairanga i te whanaketanga o te edema. Ngā tupato i roto i te maimoatanga o enei taero Me ki hei iwi e mamae i te kore uaua ngakau me te pēhanga toto tiketike. kia mutu tango "Celecoxib" tarukino ki reira he tohu o te huamo o te kopa.

kia Tūroro ki coxibs disorders tākihi maimoatanga e haere tahi i te mātakitaki tonu o ratou tohu matua.

A, no te maroketanga tango i te tarukino he taea i muri i anake te rehydration akoranga rehydration.

Reception "celecoxib" tarukino antipyretic tika ki mahi arata'i ki pōauautanga o te taupū tātaritanga, rite faateiteihia e te pāmahana i roto i te whanaketanga o ngā āhuatanga hopuhopu.

Ko te mahi o te tarukino kia meinga abnormalities i roto i te ate mahi, rawa i roto i te iwi ki mua-ngā disorders o te ate. tohu Taumaha e pā ana ki kakā fulminant, ate nekrozomtkaney. Taua tikanga puta tonu, engari i muri i anake 30 ra i muri i te tono "celecoxib" faaineineraa. Na e hiahia ana koe ki te aroturuki i mahi i roto i te maimoatanga o te ate tenei whare, a i roto i te take o te mate taimaha kia tere te whakakore koe te whakarite.

Reviews mo te maimoatanga o "Celecoxib"

kawea Nonsteroidal taero anti-inflammatory te anake i runga i whakahaunga. He whakauru nga hua o te whakamahi o "Celecoxib" arotake tarukino o tona mahi. tauturu Kotahi rongoā ki te akakoromaki i ngā tukanga inflammatory i roto i te hononga, hoki ētahi atu ko reira whai hua, me te ai he maha o ngā kino.

Ka rite ki te arotake atu tūroro te tarukino "Celecoxib"? tohu Reviews he maha o ngā raruraru: mamae i roto i te kopu, tākihi, disorders paheketanga. tūroro taua rata whakahaere whakakorenga medicament me vahe maimoatanga kē.

I runga anō i te whakaaro o te tūroro ki runga ki nga pānga o raau taero i runga i nga hononga matia, e taea te faaoti i te reira e ko te reira whai hua i roto i te whawhai ki rumati. Hei whakakore i te tohu mamae, pupuhi o te kopa i roto i te wāhi kua pā o te āhua tonu, he tūroro i roto i te ngahuru me te auau puna o te tarukino therapy "Celecoxib". Kei te whakamahia te reira i na kaitäkaro i roto i te whētuki me te hononga.

Rawa mahi tōtika medicament i roto i ngā ki painaina hinu, me hāpiapia mō te tono wā. Heoi, kia rite ki te kupu tohutohu i roto i roto i te tohutohu mō te whakamahi i homai NSAID whakamahi akoranga poto, i roto i te tikanga ki te karo te ahotea i runga i nga whatukuhu, ate, ngakau, me te puku. Kore kore ki te karo i rahunga i te mahi o enei tinana.