Agglutinin agglutinogen me - te pūmua toto, te ora-ora

Agglutinogen - he pūmua toto. I hanga i antigens kē i roto i te toru o te whanaketanga fetal marama. Ko reira reira i roto i te 2, 3 me te 4 ngā rōpū toto. Kei te mohiotia te reira, kia rite ki raraunga tata, e pā ana ki 236 antigens e kua whakarōpūtia i 29 pūnaha. takoto rōpū toto e i te pūnaha 2 - abo me rH.

Ko te hanganga o te toto. Agglutinogen - he aha te mea tenei?

Ka rite ki mohiotia te, ngā o te wai, wē me te hanga e huānga toto: leukocytes, erythrocytes me platelets.

Agglyutinogeny huaina hoki antigens (Ag). e kitea i roto i ngā pūtau katoa o te tinana ratou. hiahiatia ratou tiaki te wahi katoa. Ahakoa i roto i te roro. E hoki antigens i runga i te mata i roto o erythrocytes. A i o ratou pūtau toto ma (90 momo) agglutinogens.

Agglutinogen - he matū e pupuri ana i te manene, me te ira tautuhi i te mōhiohio tauwhāiti takitahi, me te taunekeneke ki te paturopi.

Na roto ratou natura matū, kua wehea ki:

• pūmua (rH pūmua Colton et al.);
• glycoproteins (Lutheran);
• glycolipids (avo).

Agglutinogen - he gamma-globulin, tuku nei ki te hou i te tupu. Ia, me ki he hakari wē agglutinin whakatau te momo toto, rite ka kia kōrero i raro nei.

Taumahi agglutinogens me agglutinins

Ki te agglutinogens, ko ratou te taua antigens riro i te mau metua, te agglutinins (paturopi paturopi ranei) e whakaputaina i roto i te tuatahi o nga tau o te ora. synthesizes te reira i paturopi o te pūnaha ārai mate, a ratou taunekeneke anake ki te antigen mo e e te tikanga e ratou.

E e kukume mai paturopi te whakautu ārai. agglutinate ratou (i roto i te kupu atu, kāpia) pūtau koiora, me te kia e ngaro ratou. Na e Nā enei kūtai ki ki ngā pūtau tangata ke mate, me te ngāwari excreted. He antigens hoatu ratou te mōhiohio e tika ana katoa. Na agglutinogens, whakaorangia agglutinins toto te tinana i te whakaekenga o tinana ke. Te kore ratou taiao mahi oranga taea.

rōpū toto

Kitea e te aroaro rōpū ranei otstutstvie antigens me paturopi. Antigens nui atu. Heoi, ko te nui tino mo rata antigen A ko B, me te paturopi Arepa me Beta.

He āhuatanga nui te rua o te toto tangata ko rH toto pūmua, ie. E. Ko tōna aroaro ngaro ranei.

Na wehewehe rōpū toto; agglutinogens me agglutinins tangohia ki te whakarōpū anake te hunga e e hāngai ana ki te agglutination.

Hei tautuhi i tētahi rōpū, te kawe i roto i te wheako taua. A, no te puta Mixing sera (ranei e kore e) te agllyutinatsii tauhohenga. I roto i tenei tauhohenga, ka faaoti.

Agglutination - he tauhohenga i roto i nei piri tahi, ka hinga paturopi me antigens kore e hototahi ki ia atu nei. Hei tauira, erythrocytes agglutinogens rōpū 2 toto ngā ki paturopi ki peta wē. Ki te paturopi tenei hinga toto Arepa, e ratou hononga. mate Pūtau. He taka peta antibody ki te ngongo ki te toto serum he antigen B, ano he "whakarewatanga" te tauhohenga i mua.

rangahau History

rōpū toto Tuatahi whakaritea e te pūnaha abo. tupu tenei i roto i te 1901, ka kitea Karl Landsteiner paturopi. Ko te whakarōpū o whakawhanakehia Karl Landsteiner ko J. Jansky. faaoti ratou e agglutinogen - ko te korakora tenei, i waho te matauranga o nga āhuatanga i te mea e kore e taea ki te haere tonu ngā ki te huhu. Na haere tonu tatou ki te mahi i roto i tenei aronga. I te tau 1903, motuhia te rōpū i roto i 4.

A i roto i te tau 1940 kitea A. Wiener ko K. Landsteiner te tauwehe rH. kitea ana tēnei pūmua te i roto i te āhua 85% o te iwi ki te kiri ma. Ki te pūmua prisutstveut i roto i te toto, ko rH pai (rH +), a ka kore e wātea ana - tōraro (Rh-). Mai Whakaröpütia rōpū toto i runga i te pūtake o ēnei pūnaha e rua.

ture huhu

huhu toto, ara i roto i to tatou wa, me te mohio hauora katoa o to matou tau, ko reira kino. Na roto i te huhu e haere ki anake ka he 25% ranei ake o te rōrahi katoa mate toto. He maha ngā pūmate - wheori posttransfuziozny ru - tetahi.

E ngana ana ki te kitea te toto tino tika, te kore kia meinga ai pōauautanga huhu. Ahakoa te mea i mohiotia pai e te iwi ki te 1 rōpū - te kaituku ao, ano ki te transfused te rōrahi o te toto, kaua nui, he reira pai ki te paopao ki te rōpū toto. Ko te taua pā ki te iwi ki te rōpū 4, e ko te kaiwhiwhi mo te tahi atu rōpū.

rōpū 1 pāpāho ïa no te mea e karangatia e ratou kaituku-pūkenga e toto nui huhu agglyutinogeny ngaro. I muri i te tauhohenga agglutination i roto i tenei take e kore e ka.

I roto i te whānui, i te ture he huhu ohie. Otiia nga pānga o mua huhu-e kore tetahi e taea te mea. kia agglyutinogeny huna ai te toto, a ka kua veroyatnst e kore ratou e whakakitea i roto i te tātari. Na ka kua mate te tangata i muri i te huhu o buka toto nui i te ru. Otiia e hiahia ana tona rōpū ki te mohio rite te tangata ia me, o te akoranga, ki te mohio te aroaro o te pūmua rH.

Rh Factor me Pregnancy

Ki te mea tetahi wahine he pūmua kino rH toto, e te tikanga e te wā hapūtanga taea meinga raruraru. Ko te tamaiti ki te aroaro o tenei pūmua ka waiho hei ahanoa ke ki te tinana o te whaea.

e kore Kia wahine noa tūtohutia ki te haere mo te tangata e whai i te pūmua rH. ka whakangaro paturopi Mother o fetal pūtau toto whero. I muri i te katoa, nga agglutinogen - he wāhanga o te "pūnaha whawhai" i runga i ngā pūtau e titiro ki a ratou e te tangata ke.

A, no te makimaki papā he pōauautanga taea:

• mate Hemolytic o te tamaiti;
• jaundice i whanau;
• materoto.

Otiia, ki te mea te wahine, ko te ki te tango i te tiaki o koe, ka kia raro i te mātakitaki o kaiwhakaako tonu, ka e whanau tino hauora te tamaiti.