Whakawātea creatinine

I roto i te rongoā hou, te wā "whakawātea", e tohu ana he tohu tere purenga ine etahi fluids koiora. Mā te tenei tohu kua tino whakawhānui i to tatou māramatanga o nga pharmacokinetics me pharmacodynamics o enei, me te tahi atu matū.

Ko te kupu, hei tauira, takoto creatinine whakawātea te whakamahi i whakamātau tātaritanga Reberga-Toreeva. E tano ia tapao e i roto i tenei take, ko te reira taea ki te whakatau i te auau filtration rite te taonga endogenously synthesized ka tukua i te waho (mo ngā rongoā me ētahi atu tikanga). whakamana i whakarite ai e te tātai i te tātari kaha (glomeruli) o te auau tuku wē i te taonga ngā. tū te pūkete e i roto i te wa i whakaritea (te nuinga - ra).

Korero o creatinine, kia whakarongo ki te meka e tango i te reira i te tinana, ko te nuinga e tika ana ki te mahi filtration o nga whatukuhu. I runga i tenei, pēnei i te auau whakawātea creatinine e kia nui i roto i te aro mātai o tākihi mahi glomerular filtration. Me kï reira e te āhuatanga tenei ahua te kore anake te kaha mahi o te pūnaha tātari, engari ano hoki etahi atu tauwhatinga o whēkau me ngā pūnaha tangata. Whakarerekētia whakararo, creatinine whakawātea me te kia tohu o te rere toto takarepa ki te whatukuhu (atherosclerosis, a ki te koi whakapeka, me te whanaketanga - thromboembolism).

Ko te tere o te heke o te mahi tākihi puta i muri i wha tekau nga tau. Whakaiti auau filtration glomerular o 1% ia tau. I muri ono tekau nga tau, heke te taumata o te mahi kei te paku tere (e matua hono enei huringa ki te hoholo o te rauropi). Heoi, kia tuhia te reira e kore te tetahi faaiteraa o te huringa taua kitea mo te take e te tērā i te ruhiruhia iho tukanga pūkoro tinana katoa, tae atu i te kōtuitui o creatinine endogenous.

A, no te faaineine hoki te tauira, ko te tika Rehberg ki te aukati i te whakamahi o etahi raau taero e taea pā i te akoranga o te ako (taero "cortisol" "Furosemide", "Corticotropin", "Methylprednisolone," "Thyroxine" me ētahi atu).

Hei hoatu i te tauira o te mimi tīpako te whakamana, me te te whakamātautau i runga i te taumata toharite o te wē creatinine toto.

I roto i te tohu mo te whakaaro ako: māuiuitanga endocrine, aromatawai o te mahi mahi mate täkihi, me te te aromatawai o te pānga o te mahi tinana.

Tei runga i te taumata o te whakaiti i roto i te whakawātea tautuhi enei atu ranei maumaui.

• 30 ml / min / m2, me te 1.7 - hekenga i roto i te mahi tākihi i āhua;
• 30-15 ml / min / m2 1.7 - aroaro o täkihi (ranei utua tohu subcompensated);
• <15 ml / min / m2 1.7 - wāhanga decompensation täkihi.

He mea nui ki te mahino e te kaha mahi o te pūnaha filtration whakatau whakawātea tākihi o creatinine, te tere o nei i roto i te tauira Reberga tohu whatukuhu noa.

Heoi, e kore e te tahi mau mate arahi ki huringa o te tohu (hei tauira, pyelonephritis ma'i).

taumata creatinine i roto i te toto tei runga i te mahi o tona kōtuitanga endogenous me runga i tona tere o excretion mimi. He mea nui ki te matau, e kore tenei ahua tei anake i runga i te mahi o te pūnaha tātari, engari ano hoki i te tere me te rōrahi o te reabsorption o matū i roto i te hanganga o te mimi tuatahi.

Ko te kupu, tēnei wā Reberga tauira ki (te whakatau i te waere creatinine) nui kitea whakamahi whānui i roto i te rongoā tātaritanga. He hononga tika i waenganui i te whakawātea me te tākihi mahi whakarato nui tukanga auraa tātaritanga.