Taiki Antidiuretic (ADH). Ko te secretion o ira antidiuretic

Vasopressin - taiaki antidiuretic - whakaputaina e te hypothalamus, kei nei i roto i te rapae o posterior (neurohypophysis). Tenei taiki fakapapau'i homeostasis i roto i te tinana tangata, te pupuri toenga wai. Na, mo te tauira, maroketanga toto nui ranei i raro i te mana o te vasopressin ngā tikanga ki te whakarite e te mutunga o te mate inu. Ko te kupu, ko te taiaki antidiuretic (ADH) noa e kore e tukua ki te maroke tatou.

Hea synthesized ADH te?

taiki Antidiuretic whakaputaina i roto i te neurons pūtau nui o karihi supraoptic o te hypothalamus me herea ki neyrofizinom (kawe-pūmua). I tua atu, whakahaua ana e ia ki te taupa muri o te hypophysis me reira kohikohi i runga i neurons hypothalamic. Ka rite ki hiahiatia i reira tomo te reira i te toto. pānga ADH secretion e:

1. pēhanga toto (BP).
2. te osmolarity wē.
3. Ko te rōrahi o te toto huri i roto i te tinana.

pānga koiora o te taiaki anti-diuretic

A, no te nui pēhanga toto secretion o taiaki antidiuretic tāmia me kōrero, ka taea e te nui haere te hinga i roto i te pēhanga toto e 40% o te kōtuitanga vasopressin tonu i te whakaritenga mua rā o 100 nga wa.

Kei te pā tika te osmolarity wē ki te hanganga kawehiko o te toto. Kia taka te osmolarity o toto i raro paerewa manakohia mōkito, tīmata ake te tohatoha o vasopressin ki te toto. Ki te hua i roto i te wē osmolality runga ake te tikanga tangata whakaaetia matewai. He whakamahi o ngā rahinga nui o te wai Kōpeke te rerenga o te taiki. Ko te kupu, kawea te tiaki kei te roto e te maroketanga.

Kia pehea te antidiuretic taiaki pānga te huringa i roto i te rōrahi o te komuhumuhu toto? Ki te Kei nui mate toto receptors motuhake i roto i te marae maui, ka huaina volyumoretseptorami whakautu ki te hekenga i roto i rōrahi toto me te pēhanga toto taka. Tenei tohu tomo te piki vasopressin neurohypophysis me te ora. Te taiaki puai mahi i runga i oko toto, me o ratou receptors iti mai te lumen. whai wāhi ana tēnei ki te mutunga o te toto, me te atu ārai te maturuturunga iho i roto i te pēhanga toto.

Maumaui o te ariā me te secretion o ADH

kia pā ana ēnei disorders ki te maha iti o te vasopressin tona taikaha ranei. Hei tauira, ki te mate huka insipidus reira ko te taumata iti o ADH, i te syndrome Constantin Ion Parhon tona maha atu.

insipidus huka

I roto i tenei mate, reabsorption tākihi o te wai heke tino. Ka taea te whakahaerehia i tēnei i te rua huru:

1. secretion tika o te vasopressin - ina tae mai te reira ki te mate huka insipidus o te take mai pokapū.
2. Heke tākihi whakautu ki ADH - tupu tenei ka he puka neurogenic o mate huka insipidus.

Tūroro mate i tenei māuiuitanga diuresis rā kia tae 20 rita. Mimi i iti-kukū. E tonu matewai tūroro me te inu ratou i te rota o te wai. Hei kitea i roto i te mea ahua o te puka o te mate huka insipidus manawanui mamae, te whakamahi i te orotahi o te vasopressin taiaki - he tarukino "Desmopressin". whakaaturia te pānga haumanu o te tarukino te anake i te ahua pokapū o te mate.

syndrome o tika secretion taiaki antidiuretic

Kei te karanga a hoki reira syndrome o secretion tika o ADH. tahi te mate e secretion nui o vasopressin, i reira te mea he iti kaha osmotic o wē toto. Ko te kupu i reira ko te tohu e whai ake nei:

• aitua, uaua me cramps.
• Whakapairuaki, kore o te hiahia, ka taea ruaki.
• lethargy pea, pōroa.

huru manawanui ino roa, no te te inu tinana (pâmuhia ranei ki te inu). A, no te te rāhuitanga nui o horomanga inu, me te whakakorenga e whaowhia rō-uaua i roto i te tūroro ki te murunga.

He aha tohumate tohu te taumata iti o te vasopressin?

Ki te synthesized taiki antidiuretic te i roto i te supply poto, kia wheako iwi:

• Tino matewai.
• urination auau.
• Maroke o te kiri, i te ahu whakamua tonu.
• Te kore o te hiahia.
• Raruraru ki te wahi gastrointestinal (gastritis, colitis, kōroke).
• Raruraru ki te ao fakasekisualé. Ko te tangata - mananga iti i roto i nga wahine - disorders paheketanga.
• ngenge ma'i.
• Nui haere te pēhanga intracranial.
• kite iti.

Ka rite ki tohua e te heke o ADH?

Whakaitinga i roto i te vasopressin toto kia puta i roto i te mau huru e whai ake nei:

• insipidus huka Central.
• syndrome Nephrotic.
• polydipsia Psychogenic.

He aha e nga tohu ira ki nui haere secretion o ADH?

• diuresis iti rā (mimi production).
• Taumaha taonga i te hiahia iti.
• Lethargy me te whanoke.
• Pāhoahoa.
• Whakapairuaki me te ruaki.
• cramps uaua.
• pāpaka Various o te pūnaha io.
• raruraru moe.

I raro i te mea tikanga te hua i kitea ai i roto i te taumata o ADH?

Ko te hua o te vasopressin kia kitea i roto i pathologies āhuatanga e secretion nui o te taiaki, ngā ratou:

• Julien-Barre syndrome.
• Taratahi porphyria whakapeka.

I tua atu, ko reira taea i raro i nga tikanga e whai ake nei:

• puku roro (tuatahi metastases ranei).
• mate hopuhopu o te roro.
• mate iaia o te roro.
• kiriuhi Tuberculous.
• Kakā.

taiaki Antidiuretic - kei hea tukunga?

Ko tētahi o nga tikanga whai hua tino mo te faaotiraa o ADH i te toto, ko te radioimmunoassay (Ria). Faitatau ki te whakatau i te osmolarity o wē toto. Ka taea te mahi te tātari i roto i tetahi pokapū mātai repe. mahi hoki maha haumanu tūmataiti taua tätari. Toto mahi i te rua ki korere, kahore tetahi korotutu.

I mua i te tuku o te toto ki te taiaki antidiuretic kia 10-12 break haora i roto i te kai. ahotea tinana, me te hinengaro i runga i te mahana o te takoha toto e taea ketia te tātari. e kore te tikanga tenei i te ra i mua i te tuku o te tātaritanga he mea tika e kore e ki te whai wāhi i roto i te mahi ā-tinana taimaha, e kore e ki te whai wāhi i roto i ngā whakataetae hākinakina, he ki te tango i whakamātautau, me ētahi atu

Drugs e taea te whakanui ake i te taumata o ADH, kia memeha. Ki te kore te mea taea tenei mo tetahi take, he tika nga puka tono ki te whakapūtā he aha te tarukino i whakamahia, ka me i te mea horopeta. Ketia te taumata tūturu o ADH taea te raau taero e whai ake nei:

• estrogens;
• moe pire;
• anesthetics;
• tranquilizers;
• "Rehunanu";
• "Oxytocin";
• "Cyclophosphamide";
• "Carbamazepine";
• "Vincristine";
• "Hlorpropamid";
• "Chlorothiazide";
• "Pākawa waro lithium".

Ka taea e Tātaritanga o taiaki antidiuretic kia kore mua tangohia atu i te kotahi wiki i muri i te ehu iratuke rangahau radiological ranei.

Tenei ako taea ki tatou rerekëtanga insipidus huka nephrogenic me rapae o huka insipidus me syndromes āhuatanga e secretion nui o ADH.