"Sumatriptan": tohutohu mō te whakamahi, arotake. analogues Drug "Sumatriptan"

He aha te tikanga o te tarukino "Sumatriptan"? Ka tohutohu hoki te whakamahi o te raau taero, tona mahi pharmacological, me te ahua o te hanganga, ka te aroaro he iti atu. Ano, i roto i tenei tuhinga ka korero matou ki a koutou e pā ana ki te mea i te contra-tohu me ngā pānga taha o tenei tarukino he, he aha ona tikanga o te tono me te inenga, ki te i ia tetahi analogues me pera atu.

Ko te hanganga o te rongoā me tona Composition

I tēnei wā, e taea pire anake kia kitea i roto i pharmacies me nasal rehu "Sumatriptan". Tohutohu mō te whakamahi o tenei taputapu whakarato mōhiohio oti i runga i te hanganga o te tarukino. Familiar ki reira ka waiho koe taea ki te inaianei.

Kei roto te papa kiriata pani te taonga kaha pērā i sumatriptan succinate. Ki te whakaaro ki nga mea timatanga ngaahi houalotú, ngā enei te whai ake: konupūmā hauwai Phosphate dihydrate, microcrystalline cellulose, giproloza (Klutsel ranei LF hydroxypropylcellulose), stearate konupora, mannitol (mannitol ranei), te konutai croscarmellose (ranei primelloza).

Ko te nasal whakauru kaha rehu "Sumatriptan" tavini hoki sumatriptan. Ko te wāhanga pŭpŭ tauturu, e taea te puta ke ratou rite ki te āhua o te tuku medicament. Me kï reira e whakamahia te rehu te ki hamani tawhiti iti noa atu i te papa. Heoi, E ratou ratou ake kiritaki. Ka rite ki te tikanga, ko nga tūroro kahore e nei whakamarie tango i te rongoā waha enei.

Ko te āhuatanga pharmacological o te tarukino

He aha ngā āhuatanga e papa "Sumatriptan", e arotake titiro tatou atu?

Ka mea te faaineineraa Ko te tikanga he protivomigrenoznoe. Ko te agonist motuhake, me te whiriwhiri o receptors 5-HT1-serotonin, e kua paetata i te toto oko o te roro. Me kï reira e te raau e kore pānga i runga i te tahi atu momoroto o receptors 5-Te Henare-serotonin.

I muri tango i te raau taero ai reira vasoconstriction no kakī matua moenga. Ko te kupu, ko te medicament "sumatriptan" (papa) kaiwhakawhiwhi toto intracranial me te kopa extracranial. Me kï reira e te reira vasodilatation meningeal, me o ratou puku, me he take o te migraine i roto i te tangata.

E kore e taea e tatou te mea e muri i te whakatamarikitanga o tenei taputapu e kore pānga nui (tōraro) i runga i te rere toto kaka. Papa anake tautāwhi i mahi receptor o muka afferent (ratou kūmuri) o te karere trigeminal, kei nei i roto i te Rura. puta tenei e tika ana ki te heke o te tuku neuropeptide tairongo.

kia hoki kia mea te reira e te tarukino "Sumatriptan" me "Sumatriptan Teva" tino faaore photophobia me whakapairuaki, e kua hono tika ki whakaeke migraine.

Ko te whai huatanga o te tarukino

Kia pehea te hohoro mai te pānga pai i muri i te whakatamarikitanga o te "Sumatriptan" tarukino? Mua o tenei medicament Kei roto i ngā mōhiohio e haamata te tarukino ki ngāue muri anake 30 meneti. Ko te kupu e tango i te manawanui he horopeta o 100 mg. Ratau, i roto i te 50-70% o tūroro e hohoro whakakorea migraine patua i muri i te whakamahi 25-100 mg o te tarukino. I roto i te ra, i te 1/3 tūroro matahoki, e titau te whakamahi toutou o te tarukino.

Pharmacokinetics

tarukino "Sumatriptan" Kia pehea te roa e riro? Kei te kitea hoki te whakahoki ki tēnei pātai i roto i te tohutohu mō te whakamahi o moni. I muri i te fariiraa i te tarukino roto, ia riro tata tonu i roto i te wahi kūnatu. I muri e pā ana ki 45 meneti te kukū o tarukino i roto i te serum toto tae e pā ana ki 70%.

Nā ki te absorption oti, me te tuatahi-haere pākia, te bioavailability tino o te tarukino, i te whakahaere i runga i toharite 14%. Na i runga i here ki pūmua toto wē, ko reira te tino iti (e pā ana ki 15-21%). Ko te wa hawhe-ora ko e pā ana ki te 2-haora. ahu takanga nuinga i roto i te whatukuhu.

Absorbability o te tarukino i roto i ngā āhuatanga haumanu motuhake

E ai ki te toi, e kore e patua migraine tino pā te absorbability o te sumatriptan kaihoko hohe (i ingestion whakahaere intranasal ranei).

Ki te ohorere te manawanui te ate mahi, ka i muri i te whakamahi i te rongoā kia wheako ia he nui haere te taumata o te whakauru kaha i roto i te wē. puta tenei rite ki te hua o te whakaiti i te waere tuatahi-haere.

Tuhinga mō te whakamahi o ngā rongoā

I roto i ētahi wā, kaitūtohu "Sumatriptan"? Tohutohu mō te whakamahi o te raau taero ta e kia riro te reira anake ki faaiteraa o migraine (kahore koreutu ranei ia).

Contraindications ki te whakamahi o

Ki te mea i reira e ine te tino riria reira ki te tango i rongoā "Sumatriptan" analogs o tenei tarukino? e hiahia ana ahau ki te fakamamafa'i e i roto i tenei whakaaro i roto i te tohutohu i reira ko te nui nui o te mōhiohio. Ko te aha i mua i te tango i te raau taero ki reira, kia mohio ki te pānui i.

Na te mea e kua whakaaturia te raau taero te contra-tohu? A feruri i te rārangi e tika ana inaianei:

• nui haere te tūtohutanga o te manawanui ki nga mea timatanga o te waihanga;
• tūroro ruhiruhia (i runga i te 65 tau);
• basilar, oftalmoplegicheskaya puka hemiplegic migraine ranei;
• fariiraa tukutahi o te medicament ki medicaments i roto i ergotamine me ona ngā pärönaki, me te inhibitors Mao (rāhuitia i te tikanga te fariiraa i mua ki te 14 nga ra i muri i te withdrawal o mea taero);
• mate ngakau coronary, a whakapae ai;
• hongofulu me tau o ngā tamariki (18 tau);
• angina, tae atu Prinzmetal angina ;
• hapūtanga me te ū;
• infarction myocardial, tae atu e rerengia ana i roto i te hītori;
• takawhita (momo whakakeke);
• takawhita (momo whakahaeretia);
• occlusive mate iatuku piringa;
• haurangi, tae atu tetahi tikanga pathological e pā ana ki te iti paepae haurangi;
• täkihi ate ranei;
• patunga āhua tūao o te rere toto haaparuparu, tae atu hītori rere ranei.

Ka rite ki whakahuatia i runga ake, e kore me te whakamahi i te tarukino "Sumatriptan" i roto i te hapūtanga. Otiia ki te mea he iti iho i te painga ki te whaea te mōrea ki te kukune, e whakaritea tonu reira ki nga wahine i roto i nga whaea kāwanatanga me te mea ngote u. Heoi, ki te mahi i te mea tenei ki te mātanga mātanga anake (tangohia te tarukino te tino i raro i tona mātakitaki). E te ara, e kore e tūtohu ana ki te whangai i tō uma pēpi i roto i te ra i muri i te fariiraa i papa mea.

Drug "Sumatriptan": tohutohu mō te whakamahi

tangohia ana tēnei raau te waha, ahakoa o te horomanga kai. Me kia inenga i roto i tenei take e rite ana ki te 50 mg (ki te hiahiatia - 100 mg).

Ki te whakatau koe ki te tono i te medicament nasal "Sumatriptan" (rehu), tona horopeta he 20 mg i roto i ia pongāihu. whakaaetia whakahaere toutou o te tarukino te kore mua atu i muri i te 2 hr.

Te inenga mōrahi rā mō te whakahaere ā-waha, ko te 300 mg. A, no te whakamahi i intranasal waihanga, he reira rite ki te rua pota o 20 mg.

āhuatanga rongoā

Na e matau ana koutou e founga ki te riro i te migraine. "Sumatriptan" (papa, me te rehu) pakari pai ki te mahi. Heoi, kia tuhia te reira e kore te te medicament tikanga mo te prophylaxis o mea ine.

Ko taea Whakamahia o te raau anake i roto i te take i reira ko te tātaritanga i roto i te feaa. I mua i te whakarite o te tarukino "Sumatriptan" tūroro ki mohiotia, me te kore pāngia mua ki migraine, me kia mohio ki te whakahaere tikanga i roto i te tahi atu tikanga neurological mōrearea te tākuta. kia hoki kia whanau te reira i roto i te ngakau e kia whakawhanake tūroro ki te tātaritanga i muri i te whakatamarikitanga o te papa ka mea disorders iaia roro.

titau te aroaro o abnormalities i roto i te pūnaha circulatory (i roto i nga tangata pakeke atu i te 40 tau, me te wahine postmenopausal) he whakamātautau tuatahi i roto i te tikanga ki te tutakina abnormalities o te ngakau, me te toto oko.

I tēnei wā i reira he kōrero e pā ana ki te takanga o maumaui o ruruku, ngoikore, me te hyperreflexia i muri i tango i te raau taero, "Sumatriptan" me ētahi atu taero i te rōpū o inhibitors whiriwhiri.

I mua a i roto i te maimoatanga ki te tarukino aroaro titau te horomanga kai tamau, me te ū ki te kai tino. Ko te kupu, kia faaore i te manawanui i koutou kai kai e Kei roto taonga tyramine (tiakarete, citrus, koukou, herewi, nati, te tīhi, he pini, me tōmato). I tua atu, he mea e tika ana ki te whakarere i te kai o inu i te kava, tae atu whero, pīataata, me te maroke waina, piari, pia.

Mahi, me te whakaū i te āhua noho hauora i roto i te whānui (e haere ana, te kauhoe, retihuka), kia rite ki te pai kia rite ki te aroaro o tetahi rauaruhe whai wāhi ki te putanga o kare pai, e ārai te whanaketanga o te manawanui tangata o whakaeke migraine.

Tohutohu i runga i te whakamahi o te ringihia nasal

ingoa hokohoko o te rehu ki te taonga sumatriptan kaha tangi rite "Imigran". He nga wahi e whai ake tenei raau:

• rawhi maihao;
• he matamata;
• puru te pātene.

Me kï reira e whakahohe rawa hohoro a kotahi anake te pātene puru te. I roto i tenei hononga e tūtohu ana e kore e ki te pēhi i runga reira kua tomo noa te matamata ki te irava nasal. Kore, ka kia haere te horopeta tonu i roto i te noa.

Hei whakamahi i te rehu nasal, kia tango i te manawanui he tūranga whakamarie, takoto iho, tu noho ranei. E te ara, i muri i tūtohutia kōhao nasal o te manawanui e ki kia horoia ki swabs miro.

Tango i te mōkihi namunamu me te tango i te tarukino mo te whakamahi nasal, me tomo te tarukino i roto i te kotahi pongāihu. Ko te tahi atu irava nasal, me aki reira he maihao ki te pakitara wehewehe nasal. I roto i tenei take, me manawa te manawanui i roto i te mangai.

Kōkuhu i te matamata ki te waihanga nasal ihu kia 1 henemita. Ko te upoko o te manawanui kia pupuri tika, e kore e ki te maka hoki hoki. I muri i taua, kia kati te manawanui tona mangai, me te hanga i te whakahā ata, me puhoi roto i te ihu, me te kaha tukutahi ki te pāwhiri i runga i te pātene puru ki tou koromatua. I roto i tenei take, kia titiro he tangata e te pātene ko te tino raru. Otiia e kore e ko te take tenei. kia rongo I roto i te werohanga o te raau taero i roto i te kōhao nasal o te manawanui he tangi pāwhiri hemo. tikanga o tēnei e kua pai te mahi te pātene.

I muri i tenei tikanga, e hiahiatia ana te manawanui e tona mangai ki te puaki, ka āta manawa i roto i reira. Me tonu Head ki te pupuri i tika. Next, kia hanga i te manawanui he manawa ata i roto i te kōhao nasal, a mo reira te exhale - i roto i te mangai (mō te 10-20 hēkona). e tūtohu ana e kore ki te manawa hohonu rawa.

Kia oti te tukanga ko te werohanga o te raau taero, e taea te tangata ite i te aroaro o makuku i roto i te ihu, me te reka rawakore. e kore e mōrearea ki te hauora enei sensations me te tino nohopuku haere noa. I muri i te tono kotahi o te dispenser taea te maka.

Fakatokanga ka whakamahi i

Drug "Sumatriptan Teva", e pai ki te whānuitanga nui arotake o e, kia riro te reira ki te tūpato tino ki atekōkiri o waka, me te hunga e whai wāhi i roto i ngā mahi mōrearea e rapua e nui haere tere o te tauhohenga me te aro.

pānga taha

Ka taea e whakapataritari pānga taha o te rongoā "Sumatriptan"? Teuteu o tenei ahua e taea whai wāhi ki te whanaketanga o te maha tika nui o ari kino. Kia whai whakaaro ano tatou ratou i roto i ngā kōrero ake:

• pūnaha reretoto. I runga i te wahi o te pūnaha i roto i te pēhanga toto iti manawanui kia kitea ai, infarction myocardial, pēhanga toto poto tiketike (te tikanga tata i muri i ingestion), tachycardia, bradycardia, tachycardia, a i roto i ētahi wā, arrhythmia, mamae o te iatuku pūngākau, huringa ECG tūao syndrome o Raynaud.
• pūnaha io me okana tikanga. I muri tango i te tarukino kia wheako i te tangata rohirohi, whanoke, ngoikore, me te momoe. I roto i ētahi wā, te raau taero ai diplopia, hukihuki, te takanga o te kōpura rere i mua i ona kanohi, nystagmus, heke acuity ataata, scotoma me kanohi mate rangitahi o kite.
• Ko te wahi kūnatu. Mai i te nakunaku i roto i te manawanui maha kitea ruaki, dysphagia, whakapairuaki, me te whakanui ake (iti) mahi o whākōkī ate, hūhi puku, me te colitis rere pūroto.
• Allergy. I muri tango i te raau taero, korerotia etahi tūroro te ahua o pruritus, ponana, urticaria me erythema. Ano, i reira he anaphylaxis, he mana'o o te wera, mania, me te mamae i roto i te matenga, pouri, te pēhanga, Makere, me te myalgia. whakahaere Intranasal o te raau taero e taea puta i roto i te puka o tauhohe rohe pūkahukahu ritenga tūao ranei tahu sensation i korokoro te me te kōhao nasal me nasal toto.

Ngā pāhekoheko ki ētahi atu taero

Kia pehea te mahi i te tahi atu rongoā i runga i te whai huatanga me te whai pānga o te "Sumatriptan" tarukino? Tohutohu, kōrero i nga tohunga i runga i tenei kaupapa i roto i te mōhiohio e whai ake. Ki te whakamahi tukutahi o te tarukino me te medicament "Ergotamine" me te tikanga he ergotaminsoderzhaschimi manawanui taea vasospasm roa. I roto i tenei whakaaro, i te wā i waenganui i pota o enei taero kia i te iti rawa 24 haora.

E ai ki te rangahau, i reira he he pāhekoheko i waenganui i te tarukino "sumatriptan" me inhibitors Mao. Ko te kupu iti te auau pūkoro kei te tuatahi, me ona piki kukū.

Ki te whakamahi tukutahi o mea taero anti-migraine, ka puritia inhibitors whiriwhiri serotonin reuptake, kia whakawhanake i te manawanui ngoikore, hyperreflexia me ohorere ruruku o ngā nekehanga.

Tuwhena rawa o taero (tohumate, maimoatanga)

Eaha te tupu, ki te kore koe e ū ki te inenga tūtohutia e tō tākuta? A, no te whakamahi nui o te faaineineraa "sumatriptan" tūroro kia whakapiki ake i runga ake tauhohe taha. I roto i tenei whakaaro, titau ratou huru kitea motuhake mō te 10 haora.

Ki te tika, āwhina te manawanui tuwhena rawa te i roto i te puka o te maimoatanga symptomatic.

Drug "Sumatriptan": analogues me te utu tarukino

Whiwhi te taputapu i tetahi rongoā. Me kï reira e whakaritea te utu o "Sumatriptan" o te raau taero, ki atu, āhua iti. Ko te kupu, ka whai ki te utu 170-200 anake moni Russian i runga i te 50 kiriata pani papa i roto ia koutou. Ko te nasal tikanga e tona utu ko e pā ana ki te taua.

ahakoa ritenga i te tarukino "Sumatriptan"? "Amigrenin" - he tarukino e te tino nuitia whiwhi ki te whakakore whakaeke migraine, ki te runga ake te tikanga ngaro i te rongoā te. Haunga reira, analogues medicament "sumatriptan" o taonga kaha e te whai ake raau taero: "Sumarin" "Imigran", "Sumitran", "Migrepam", "Sumatriptan-Teva", "succinate sumatriptan", "sumatriptan Pfizer", "sumatriptan Adifarm "" Sumamigren "," Trimigren "me pera i runga i.

Ano, ka rite ki te decongestants nasal rite, etahi tohunga tūtohu te whakamahi i te rehu "Imigran".

tikanga rokiroki me te ora papa

kia penapena raau Vauvauhia anake i roto i te maroke, ka tiaki i te wāhi rā. E kore e te pāmahana i roto i te piha e neke atu i te 25 nga nekehanga. Ko te ora papa o hauora whakaurunga he 3 tau. I muri i tenei wā, e kore me te whakamahi i te tarukino.