"Relpaks": tohutohu mō te whakamahi, arotake. analogues tarukino

Migraines, ahakoa kahore te ora whakawehi mauiui o te taata i te reira, engari i te wa ano tino whakaiti te kounga o te ora. Neke atu i te nga tau, kei te mahi i te ahumahi ho'oraa ki te waihanga hua e kore e faaore noa nga tohu fakamamahi o tenei mate, engari ano hoki ki te whakaawe i te tukanga e meinga te migraine. I muri i te katoa, ki te mutu taea te mamae kia painkillers kaha. Ko te tahi atu tohu o te migraine pērā i whakapairuaki, te tūtohutanga marama me te ātete ki oro, e kore e mea ohie ki te whakakore. Ko te tarukino hoki migraine "Relpaks" i roto i tenei whakaaro, tohunga te mea tetahi o te whai hua tino. He aha te mea tenei tarukino? Me pēhea te ki te tango i reira, me te aha tona ritenga i reira? koe tenei katoa e taea te pānui i runga i.

whakaahuatanga waihanga

Ko te matua kaha rawa "Relpaks" faaineineraa - i roto i te puka o te eletriptan hydrobromide roto i roto i nga papa o te 20 mg. He he ano hoki te inenga o 40 mg. E nuitia mau pŭpŭ whakamahia i roto i te reihuka monohydrate ahumahi ho'oraa, konupora stearate, konutai croscarmellose me MCC. e kore e ēnei pūhui pā te kaha o te tarukino ki te nakunaku, a e kore e pā te tinana kia rite ki te katoa. Papa o te migraine "Relpaks" pani anga membrane karaka, e kei Titanium hāorarua, colorants, monohydrate reihuka, hypromellose me triacetin.

i hanga ia pire e i roto i te āhua biconvex tawhio. I tetahi taha he mea whaowhao rawa «Rep 20» ranei «Rep 40 '(i runga i te nui i roto i roto i te papa o te whakauru kaha) me« Pfizer »- ki tetahi. I roto i te hāngai kotahi namunamu 2, 3, 4, 6 ranei 10 papa, e, i roto i te tahuri, Kikī i roto i ngā pouaka pepa 1, 2, 3, 4, 5, 6 ranei 10 nga wahi.

Pharmacokinetics me pharmacodynamics

Medicine "Relpaks" hohoro a pai whenumi muri whakahaere waha, ngā i roto i ngā ki fatty kai. Absorption tauwaenga eletriptan e pā ana ki 81%, me te pera-ka karanga bioavailability - 50%. Ko kē te ihirangi mōrahi o te taonga kaha i roto i te wē toto haora kotahi me te hawhe i muri i tango i te raau taero.

Ko te matua kaha rawa "Relpaks" teuteu he mahi pai mō te hononga ki te pūmua wē (e pā ana ki 85%). puta pākia eletriptan Paraimere i roto i te pūtau ate. Ko te kupu i hanga e rua metabolite komuhumuhu, kotahi (i hanga e N-hāora) e kore mahi. Ko te tuarua (i hanga i roto i te N-demethylation) He nuinga te taua āhuatanga rite te rauemi taketake, engari tona kukū i roto i te wē, ko te 10-20 anake% o te kukū o te eletriptan. Nā ki te metabolite hohe e kore pānga haumanu appreciable.

Papa migraine "Relpaks" whakautu o tohunga i he te nuinga pai, whai hua ahakoa o te sex o te manawanui. Kei te mahi excretion o te metabolites tarukino ki te whānuitanga nui i roto i nga whatukuhu (āhua 90%), me roto i te whēkau.

Kua whakapumautia Studies te kore o te pānga o Habituation ki te whakauru matua kaha o te tarukino, na tenei ra i reira he kore here i runga i te roanga o te therapy o te mamae migraine mā te whakamahi i taero "Relpaks".

Āhua pharmacodynamic tarukino "Relpaks" tono Kaiwhakamahi faahiti te meka e tona taonga kaha matua no ki te rōpū o whiriwhiri iaia serotonin me receptors neuronal, puai pānga i runga i ētahi atu momo o ratou. Ko te kupu whakakitea selectivity te ki te whānuitanga whanaunga nui ki te receptors kei roto i te pera kakī. Protivomengrinoznuyu mahi eletriptan whakatau kore anake tona kaha ki te whāiti o te oko toto kei roto i te pakohu roro, engari ano hoki he pānga pai i runga i te āhua o te mumura neurogenic. I roto i tenei take, i te taonga kaha e ngā kahore pānga i runga i te mau farii ohipa o te femoral me iatuku pūngākau.

iteraa papû

E tūtohutia Drug "Relpaks" tohutohu mō te whakamahi i roto i nga momo e rua o migraine:

1. Ki te koreutu, ka tapiritia ki te tohu mamae kino pērā i ataata, tūturu, motor, olfactory me disorders māna.
2. Kahore koreutu, ka i roto i tua ki te ānini manawanui mo whakapairuaki, ruaki, te tūtohutanga ki te marama, me te tangi.

Ki te mea i reira e te tahi atu mau huru o te mate te whakamahi o te tarukino kore anake e te pānga pai, engari kia meinga ano hoki e rave rahi pōauautanga. Na reira, i mua i te whakamahi koe i tēnei rongoā ki te whakakore i te ānini, migraine, e hiahia ana koe ki te kōrero i te tohunga, me te amohia e whakamātautau taipitopito. Te reira e tauturu kore anake ki te whakahau tika maimoatanga, engari ano ki te whakakore i te mōrearea tonu ki te hauora o te manawanui.

contraindications

A feruri i te rārangi o contraindications mō te whakamahi "Relpaks" tarukino. Papa, rite whakahuatia i runga ake, i roto i eletriptan e he ahei o pānga pūnahanaha i runga i te tukanga maha rauropi me awe. I roto i ētahi wā, te whakamahi i te hua Kāore houhou ranei:

• i roto i te aroaro o te rauangi teitei o te manawanui ki matū katoa hanga wahi o te tarukino;
• i roto i disorders o te ate, me whatukuhu, rite pākia me excretion o te whakauru matua kaha puta i roto i a ratou;
• ki te takawhita whakakeke;
• ki mate moe hou pikikaa ranei o te ngakau, tae atu i te whakaeke ngakau, angina, mate te AVC;
• i roto i te aroaro inklyuzionnyh mate iaia piringa;
• ka whakawhitia ranei ngā i te kau o te whakaeke rere pūroto rangitahi, me te tetahi takahi o tohanga kaka.

Drug "Relpaks" hua'tu kore tūtohutia hoki tangata nei tau he iti iho i te 18 tau. I tua atu, e kore e taea te whakamahi i te tarukino kia whakaorangia o te mamae e pā ana ki pāhoahoa pērā momo migraine rite basilar, ophthalmic me hemiplegic.

Whakamahia i roto i te hapū, me te hohipera

Kua kua iti rawa ako Whakamahi o te tarukino "Relpaks" i roto i te hapūtanga. Heoi, rangahau taiwhanga i roto i nga kararehe tohu te pānga o eletriptan i runga i te kukune whakawhanake. Tuatahi, kitea he maha iti o ira mutated (rite ki te parau tumu o te polyploidy) i roto i te ira. Tuarua, ko tino raro atu i roto i nga kararehe i kore e riro roto i te hapūtanga eletriptan te wā-tonu whanau taimaha. Ko te aha tohunga i roto i tona tikanga whakarite arahina, i te mea e te painga e tūmanakohia ki te whaea e tami te heke mai taea ngá ki te kukune. Me kï reira e eletriptan wahi o te raau taero i kitea i roto i te waiu tangata, ara i muri i nga ra i muri i fariiraa,. Na reira, ko te whakamahi o te rongoā i te u, he taea anake i roto i te take o te kore ki te ū hoki i te iti rawa i te ra.

pānga te taha e pā ana ki te whakamahi tarukino "Relpaks"

whakarato mateā "Relpaks" arotake tarukino mātanga mōhiohio e pā ana ki te pakeke ngoikore o ngā pānga taha, i anake kei roto i te wā poto ngā o te wā. Aita e hi'oraa e aha te horopeta (20 mg 40 ranei) riro e te manawanui. Ko te tohu tino noa a'usia ka tango i te raau taero e:

• mumura o te kōhao nasal me pharynx (pharyngitis, me Rhinitis);
• raruraru rongo pērā i mania, "fepulopulasi kuihi";
• te momoe;
• whanoke ānini ranei;
• gravis myasthenia hypoesthesia ranei;
• hypertonicity o nga muka uaua;
• mamae ite kikī i roto i te hoki me te pouaka ranei;
• arrhythmias cardiac, i roto i ngā tachycardia;
• disorders dyspeptic pērā i te mamae ranei hūhi i roto i te puku, mangai maroke , me te whakapairuaki;
• ake i roto i te sweating;
• flushes wera Chills ranei ki te kanohi.

Ka mau ia ki pūkete te hanganga matū o "Relpaks", e kore e tohunga tutakina te whanaketanga o tauhohe mate pāwera ki wāhanga o te raau taero, e ai kia whakahuatia i roto i te ahua o te hunga ponana, minamina whero ranei. I tua atu, i roto i wā onge, kia kia āwangawanga e pā ana ki taua ari rite tūroro:

• hārukiruki;
• lymphadenopathy;
• whakama, euphoria whārua ranei, ohoroa me lability aronganui;
• photophobia, mamae i roto i te 'Afio, pīkaru, iti nui haere lacrimation ranei;
• te reka o pōrearea;
• waea i roto i te taringa, tetahi raru ranei;
• pēhanga toto tiketike;
• patua huangō;
• huri i roto i te reo reo;
• huamo i roto i te kōhao-waha;
• kōroke korere ranei;
• rumati arthrosis ranei;
• myalgia myopathy ranei;
• polyuria urination auau ranei;
• disorders paheketanga;
• colitis rere pūroto.

Ka mau ia ki pūkete te pānga taha i runga ake-whakahuatia, ki te whakamahi o te tikanga o te migraine "Relpaks" whakatenatena whakatinana i raro i te mātakitaki o tohunga, a i muri i anake nga rangahau e tika ana mō ngā mate ngā ka kawea i roto i, e taea haafifi maimoatanga.

pāhekoheko

A feruri i te pāhekoheko ki etahi taero antimigraine āpiha "Relpaks". aratohu rongoā e kei whānui ngā mōhiohio e pā ana ki tona hototahi ki ētahi atu taero e kore e tangohia tahi ki te rongoā e tika ana e whai ake nei ngā rōpū:

• inhibitors isozyme, e ngā "erythromycin", "ketoconazole" "Clarithromycin" me "Itraconazole";
• inhibitors protease, tae atu "nelfinavir" me "Indinavir".

mōhio hoki Tohunga te meka e te fariiraa tukutahi "Relpaks" tarukino rongoa "Propanolol" me "Verapamil" taea anake whakapataritari he hua nui i roto i te pēhanga toto, engari ano hoki whakarei i te mōrea o te tahi atu pānga taha. Ka taea te tūmanakohia te pēhanga toto Nui ake i roto i te take o te whakamahi tahi o te tarukino me te raau taero kawhe. Ko te aha tohunga tūtohu e te wā ia rā i waenganui i pōhiri ki o taua raau taero rite "Relpaks" (hinga ano hoki analogues i raro i tenei whakamāramatanga) me taero ergotaminopodobnyh.

Hauora, kua whakamatauria te reira e kore e nga tikanga o te migraine i te pātai i roto i tēnei tuhinga ariu ki matū e pā ana ki te beta-blockers, estrogensoderjath taiaki whakakapi te whakawhānau kōrero ranei, engari ano hoki ki te pōuritanga tricyclic.

tuwhena rawa

Ki te nui koe te nui rata tūtohutia o tarukino faaara "Relpaks" ā-ako o te tuwhena rawa, e ai meinga hua tamau i roto i te pēhanga toto, me te tahi atu disorders o te pūnaha Cardiovascular. A, no te puta ratou, ka tūtohutia maimoatanga symptomatic te ki te lavage pekitīlia tika.

dosing

Drug "Relpaks" tohunga tūtohu tango i te timatanga o whakaeke migraine. Ki te haumi i te ānini, me ētahi atu mau ma'i whakararuraru i reira te manawanui mō ētahi hāora, rite te tarukino te mau tonu tana whai huatanga. Me kï reira e fariiraa o tarukino rite te kaihoko ārai mō te migraine he kaore e, mai i te whakamatauria ai e i roto i tenei take e kore e whai i te reira i te pānga e hiahiatia ana. I te wa ano, ka tata te koreutu (tūroro, ka taea e tūroro migraine wā roa-tautuhi tenei huru) tango i te tarukino kore anake whakaiti te mamae e whai te koreutu, engari relieves hoki tohu pērā i whakapairuaki, momoe me te photosensitivity. e kore tenei puta kotahi, engari i muri i anake te tīmatanga o pāhoahoa. Na reira, e kore e tūroro migraine rere ki te inu i te pire i ia wa he aorangia hoki.

Ko te horopeta tuatahi o te tarukino mō tūroro 18-65 tau o tau ko 40 mg. I muri i te tanga o te mamae migraine taea te anō. I roto i tenei take, taunaki te aratohu tango ano te raau taero i te inenga kotahi, engari e kore e wawe atu i te 2 haora i muri i te fariiraa tuatahi. I roto i te take o te kore o te tarukino, i te tenatia ānini i roto i te 2 haora i muri i te whakahaere tarukino, e kore e anō-tango horopeta tūtohutia. tohu nga tohunga i roto i e taea te tāmau i te whakaekenga i muri o te migraine i roto i te manawanui taua tuatahi horopeta "Relpaks" tarukino. arotake Kiritaki i runga i tenei take i roto i hoki rite mōhiohio.

Ko te horopeta mōrahi o medicament riro i roto i te ra kotahi e kore e nui ake 160 mg. Inu papa kia katoa, kahore ngaungau, nui o fluids inu.

Ara

Ko te whakamahi o "takanga Relpaks 'he taea i muri i anake te haamauraa o te tātaritanga o" migraine ". Ko tenei e tika ana ki te meka e ka pāhoahoa mohiotia, e taea hoki e te meinga e patu, aneurysm whaturama me ētahi atu mate nui, tona whakarite taea tīmata ngā pōauautanga. I tua atu, he mea houhou ki te whakamahi i tenei tarukino ki te whakakore te mamae kino i roto i te migraine i rotopu mate Cardiovascular me disorders o te tākihi me te ate, rite tenei e taea te meinga te pēhanga toto tiketike ki te taumata tino. Ko te taua pā ki tūroro i roto i nei te mōrea o te whakawhanake i mate Cardiovascular he tiketike. Ko te aha i mua i tuhituhia i te tarukino "Relpaks" kia amohia e te manawanui he whakamātautau tonu. kia Tūroro i roto i te whakamahi i runga i te 65 tau o te raau taero i raro i te mātakitaki o tohunga, mai te mea e ratou tino pinepine kitea hua i roto i te pēhanga toto.

Whakatūpato! No nia i te fariiraa o te tarukino "Relpaks" ā-ako kei tohutoro ki taua pānga taha rite whanoke me te momoe, na kia kia koe rawa tupato ka peia waka me i roto i te whakahaere i te hangarau matatini.

Analogs "Relpaks" utu tarukino

Ko te nuinga o taero whakaputaina e kamupene ho'oraa i roto i te Te Hau-ā-uru, i reira he ritenga kāinga. Ka taea e tatou te kōrero e pā ana ki a ki Pfizer - kaihanga "Relpaks" tarukino. Heoi, mai i rēhita reira tata anake, ki te rā i reira he kahore taero e pai ai kia te taua āhuatanga rite te tarukino "Relpaks". Analogs matua eletriptan whakauru hohe mohiotia hoki, i nei e taea te faaoti i te reira e ko ahurei te faaineineraa. tona utu i roto i Russia he i 380 ki te 1200 moni. tei te utu motuhake i runga i te maha o papa i roto i te mōkihi, me aha ratou inenga.

Na roto i te tikanga o te pānga i runga i nga oko roro i roto i nga papa "Relpaks" i reira e rave rahi ritenga, e kore e kore anake nui rerekē i ia i te utu, engari e nui atu te utu maha. Hei tauira, ka taea te hokona te rongoa mo te migraine "Zomig" i te utu o tawhio 400 moni mō te toru pire. Drugs "Imigran" me "Sumatriptan" he rite ki te hoki "Relpaksom" kua te pānga o me utu. Te raau anake, i te utu iti rawa iho i te "Relpaks" papa - he "Kofetamin". e kore e ratou utu nui 75 moni ia mōkihi.

Reviews o te faaineineraa

Na, i runga i ki te pātai tino nui. He aha ta ratou whakaaro e pā ana ki te hua rongoa "Relpaks" kiritaki me ratou taote? He aha e nga pai me ngā raruraru kua tenei tarukino? Ko te mea tuatahi e mea ratou e pā ana ki 80% o nga ngā - ko te tōtika tiketike o pire "Relpaks" ara ki te whakaeke migraine nui. Urupare i tūroro, i muri i tango tetahi noa pire haere atu te mamae i muri i te 30-40 meneti. Mō 8% o kiritaki ruritia tohu e muri i te whakamahi o te horopeta tuatahi o 40 mg i puta tohu pērā i faaati o nga wahi, me te mania i te mata, me te ringa. Heoi, ka mau enei ngā kino wahi mo e rua haora, kahore tetahi mahi atu.

Iti iho i te 1% o te tūroro e kua whakaritea he tarukino "Relpaks", e kore e te fariiraa tuatahi ite i te katoa o tona pānga. Ko tētahi-toru o ratou ina i anō-pai o te tarukino, kua tona pānga, me nga etahi i takoha ki te kitea te whakakapinga.

mōhio Tohunga i roto i nga painga o te faaineineraa o tona pānga ngawari i runga i oko toto o te matenga. Heoi, mōhio ratou e te ahua o ara nga pānga taha tino iti te manawanui kia moe tika. ka kia nui mo nga ari kino katoa o te mua tenei. mōhio hoki ngā tohunga te whai ake: i roto i te rerekē ki ngā rongoā rite, e kore e nei i te wahi o te eletriptan tarukino "Relpaks" nui māmā iwi migraine nohotahi.