Protamine pūkawa: Whakamārama me te Kaiwhakamahi

He aha te mea he taonga tarukino rite protamine pūkawa? Ka tohutohu hoki ona whakamahi, me te te āhua me te whakaaturanga o nga moni e tabulahia i raro nei.

Composition, whakaahuatanga, puka

He aha te mea protamine pūkawa? I tukua tenei otinga rite te wai mārama kowhai taekore ranei te tikanga mo te whakahaere rō-uaua. Te faaineineraa e hāngai ana i runga i tenei tarukino kua te taua ingoa, a anō kei roto i te wai mo te werohia.

I roto i te hoko o "Protamine pūkawa" e tukua i roto i te oko e kua whakanohoia i roto i te whakahuahua pūtau i polyvinyl pūhaumāota kiriata, e kua Kikī i roto i ngā pouaka pepa. i roto i te mōkihi ano whakanohoia te tohutohu mō te whakamahi, me te tīkape ampoule.

mahi Drug

He aha te mea protamine pūkawa? pūrongo Guide e tenei heparin enemi (motuhake). 1 mg o te taonga e taea o neutralizing toto o te manawanui o e pā ana ki 80-115 Iu o heparin.

Mahi pūrongo tikanga i muri i tīmata tonu i werohia rō-uaua, me te pumau hoki e pā ana ki te rua nga haora. Complexation o te tarukino tika ki te nui o ngā rōpū cationic e herea ki te heparin pokapū anionic.

E ai ki nga tohutohu o te protamine pūkawa i roto i te tangata complexed te heparin-protamine, e wawahi ki te tuku i te whakamutunga.

I roto i te tuwhena rawa te tikanga o tenei ka taea te tino heke te manawanui toto upoo-, mai whakaaturia whakaaro waihanga māngai kaha te mahi anticoagulant tiketike.

tikanga Pharmacokinetics

He aha He āhuatanga nekeneke o te pūkawa ngāwha heparin protamine? E ai ki nga tohunga, te mea kua kore i ako āhuatanga pharmacokinetic o te tarukino. Na reira, e kore e māngai ratou i roto i te buka haapiiraa.

Tuhinga mō te otinga

I roto i ētahi wā, te manawanui rō-uaua otinga "Protamine pūkawa" taea te whakaritea? whakaaturia Taupānga o tenei tikanga te:

• i mua i pokanga i roto i te iwi tango heparin mō ngā take haumanu;
• i hyperheparinemia;
• mō te toto e puta ana e tika ana ki te heparin tuwhena rawa;
• i muri i te mahi i runga i oko toto, me te ngakau ki te tohanga extracorporeal.

Rāhui ki otinga ūnga

contraindicated Drug "pūkawa ngāwha Protamine" (te whakahaunga ki te hoko me whakahau reira he tākuta) e i roto i te wā e whai ake nei:

• ki thrombocytopenia;
• tūtohutanga tiketike ki nga mea timatanga o te tarukino;
• hypotension nui;
• hyperheparinemia congenital idiopathic ranei (i roto i tenei āhua ko te rongoā hua, a taea hoki tino whakarei ake toto);
• whakahaere o te taiāki huka, me te tahi atu raau taero kei roto i te pūkawa ngāwha protamine;
• tauhohe mate pāwera ki ngā hua ika, tae atu he hītori;
• iti hoki adrenal.

E kore e taea e tatou te mea e he iti te wheako o te whakamahi hauora o tenei taputapu i roto i ngā tamariki.

I roto i te hapū me te hohipera "Protamine pūkawa" taea te whakamahi. Heoi, kia meatia tenei anake i roto i te take, ki te he tino teitei ake i te mōrea pea ki te kukune tamaiti ranei te pānga o te maimoatanga.

Te faaineineraa "pūkawa ngāwha Protamine": tohutohu mō te whakamahi

kia otinga i Tirohia kia whakahaerea e te honikoma IV puhoi bolus ranei. Ko te kupu e kore e nui ake te tere o te whakahaere 5 mg ia meneti. whakataki tere o te tarukino taea meinga te manawanui tauhohenga anaphylactoid.

Inenga o te medicament tei runga i te tikanga o te whakahaere. kia memeha e te horopeta tatau i roto i te 300-500 ml o 0.9% otinga pūhaumāota kaha konutai. Kei te tino riria ana te reira ki te tomo atu i te 150 mg o tarukino mō te 60 meneti.

• Ki te heke bolus werohia inenga o protamine pūkawa te i runga i te wa i haere ai i te whakahaere o te heparin rānei. Ko e tika ana ki te meka e te tonu nekehia te whakamutunga i te tinana tangata tenei.
• Ki te whakahaere heparin te maturuturu rō-uaua, he mea e tika ana ki te aukati i te whaowhia, me te whakamahi i pā ana ki 20-30 mg o protamine pūkawa.
• A, no te werohanga subcutaneous o heparin inenga o protamine pūkawa 1-1.5 mg 100 Iu heparin. Ko te kupu kia āta whakahaere pâmuhia te 25-50 mg tuatahi, me te rahi e toe - maturuturu rō-uaua mō te 8-17 haora. Ko reira ano hoki e taea whakahaere taratahi, engari ka rapu utu aroturuki tino o APTT.
• A, no te he wawaotanga arä i roto i te take o extracorporeal otinga tohanga inenga whakaaro he 1.5 mg ki te 100 AU heparin.

Ko te roanga mōrahi o therapy o nga moni ko 3 ra.

Mahi i-pūāhua

Ka taea e ki te pūkawa protamine meinga tauhohe kino? āhua ā-e i roto i te whānui te ngā pai noatia tenei tarukino e tūroro. Heoi, i roto i ētahi wā, ka taea e meinga tonu reira paanga kino i runga i te wahi o nga pūnaha ārai mate, Cardiovascular me kūnatu, rite pai rite te kiri:

• bradycardia, he whakaiti i roto i te pēhanga toto;
• ruaki me te whakapairuaki;
• minamina, ponana kiri, te whanaketanga o tauhohe anaphylactoid;
• ongo'i wera, mana'o poto o manawa, me te Makere o te kiri.

Overdoses me te taunekeneke ki ētahi atu taero

otinga tirohia te tikanga mo te whakahaere rō-uaua he hotokore ki penicillins me cephalosporins. Hoatu e ko te reira he enemi, iti heparins taimaha rāpoi, kia whakanui i tarukino kaha te roanga, me te kaha o te mahi o relaxants uaua kore-depolarizing.

He tuwhena rawa o te tarukino kia pā ana ki toto. Ko e tika ana ki te meka i te taonga i roto i te pātai he mahi anticoagulant tiketike tenei. I roto i tenei take, e mau ana i roto i te maimoatanga symptomatic hiahiatia te.

mōhiohio motuhake

He aha kia mohio koutou ki te aroaro o te tomo koutou he otinga pēnei i protamine pūkawa? mea Tohunga e kia kia āta aro turukihia te whakamahi o tenei tarukino i te tākuta nei me te aroturuki auau i te manawanui toto upoo-.

I mua i te whakataki o te tarukino tika ki te whakarite rōrahi toto tika o manawanui. Ko e tika ana ki te meka e hypovolemia tino whakanuia ana te mōrea o te tiango tenei.

Storage tikanga o supply o pharmacies, te ora papa

Ahakoa noa hokona i roto i pharmacies tarukino "pūkawa Protamine '? Recipe i roto i te reo Latin Russian ranei, kia mohio ki te whakaatu i te rongoā, te kore tukua te tarukino te.

whakaaro e tika ana te tikanga Rokiroki i taea o ngā tamariki, me te tiaki i te rā i reira te pāmahana rangi ko waenganui i 4 me te 10 nga nekehanga. Me mahara hoki käore te reira e kore te tikanga kia whakatotoka ana te rō-uaua otinga "pūkawa ngāwha Protamine" i roto i tetahi take.

Pa'epa'e ora o tenei tarukino ko 4 tau i te rā o te whakanao. Kaua e whakamahi i te reira tua atu i te paunga o tenei wā.

analogues Drug me arotake e pā ana ki reira

e kore e tino maha analogues i roto i te taputapu pūrongo. Ka taea te whakakapi i te otinga rō-uaua e taero pērā i "Protamine" me "Protamine-Verein".

Ki te whakaaro ki arotake kiritaki, tata katoa o ratou he pai. "Pūkawa ngāwha Protamine" - ko te tino pai, me te whai hua rawa e wātea ana ki te katoa tenei. Kei te tiri te reira i tenei whakaaro e te nuinga o te tūroro. titau ratou e kore e hoatu e tenei rongoā heparin ki tautāwhi i te tukanga o te upoo- toto, te whakapai ake huru o te manawanui i roto i toto taimaha.

Ka rite ki ki nga take o tenei tarukino ngā tona pānga tere, me te auroa. I tua atu, ki te whakatutuki i te pānga haumanu hiahiatia ki te he manawanui ki te kawe i roto i te maimoatanga wā roa-. Ko te wā mōrahi o te whakamahi o tenei tarukino ko e toru nga ra.